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Volume 13, Number 9—September 2007
Letter

Recurrent American Cutaneous Leishmaniasis

Jean-Pierre Gangneux*Comments to Author , Sylvie Sauzet†, Sébastien Donnard†, Nicolas Meyer*, Anne Cornillet*, Francine Pratlong‡, and Claude Guiguen*
Author affiliations: *Centre Hospitalier Universitaire Faculté de Médecine de Rennes, Rennes, France; †Service Medical du 11ème Régiment d'Artillerie de Marine, Saint-Aubin du Cormier, France; ‡Université de Montpellier, Montpellier, France;

Main Article

Table

Epidemiologic characteristics, strain identification, and treatment of 21 cases of American cutaneous leishmaniasis, French Guiana, 2004–2005*

Case no. Primary infection
Leishmaniasis recidiva cutis
Lesion(s), location (no.) PI treatment† Time to healed lesions, mo Disease-free interval, mo Direct examination Strain identification PI treatment Outcome
1 Thorax (1) IV, 4 mg/kg on alternate days × 3 1 4 + Leishmania guyanensis MON-45 IV, 4 mg/kg on alternate days × 4 Cured
2 Right forearm (1) IV, 4 mg/kg on alternate days × 3 3 6 + L. guyanensis MON-45 IV, 4 mg/kg on alternate days × 4 Cured
3 Left leg (1) and chin (3) IV, 4 mg/kg on alternate days × 3 1 4 + Negative culture IV, 4 mg/kg on alternate days × 4 Cured
4 Chin (3) IV, 4 mg/kg on alternate days × 3 1 4 + Negative culture IV, 4 mg/kg on alternate days × 4 Cured
5 Behind left ear (1) IV, 4 mg/kg on alternate days × 3 1 3 + L. guyanensis MON-131 IV, 4 mg/kg on alternate days × 4 Cured
6 Left ear (1) IV, 4 mg/kg on alternate days × 3 1 6 + Negative culture IV, 4 mg/kg on alternate days × 4 Cured
7 Right ankle (5) IV, 4 mg/kg on alternate days × 3 2.5 4 + Negative culture IV, 4 mg/kg on alternate days × 4 Cured
8–21 Various IV, 4 mg/kg on alternate days × 3 (for 9 patients) or IM, 4 mg/kg on alternate days × 2 (for 5 patients)† 1–3

*PI, pentamidine isethionate; IV, intravenous; IM, intramuscular.
†IV versus IM administration of pentamidine isethionate was not associated with recurrent forms.

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Page updated: July 01, 2010
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