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Volume 14, Number 2—February 2008

Dispatch

Methicillin-Resistant Staphylococcus aureus, Geneva, Switzerland, 1993–2005

Patrice Francois*1Comments to Author , Stephan Harbarth*1, Antoine Huyghe*, Gesuele Renzi*, Manuela Bento*, Alain Gervaix*, Didier Pittet*, and Jacques Schrenzel*
Author affiliations: *University of Geneva Hospitals, Geneva, Switzerland;

Main Article

Table 2

Molecular characteristics of the non–multidrug-resistant methicillin-resistant Staphylococcus aureus isolates, Geneva University Hospitals, 2002–2005*

Isolates No. strains PVL Exfoliatin toxin A TSST-1 agr type
Main MLST types
1 2 3 4
SCCmec I 21 0 0 11 9 11 1 0 5,149
SCCmec II 1 0 0 0 0 1 0 0 ND
SCCmec III 1 0 0 0 0 0 1 0 ND
SCCmec IV† 109 53 11 9 20 24 65 0 1, 5, 8, 22, 30, 72, 80, 85, 88, 149
SCCmec V 15 6 0 1 8‡ 3 4 0 1, 30, 59, 85, 152
SCCmec NT 4 1 0 1 1 1 2 0 ND
Total§ 151 60 11 22 38 40 73 0

*PVL, Panton-Valentine leukocidin; TSST-1, toxic shock syndrome toxin 1; agr, accessory gene regulator; MLST, multilocus sequence typing; SCCmec, staphylococcal cassette chromosome mec; ND, not determined; NT, nontypeable.
†Two isolates had recombinases identical to SCCmec IVe on the basis of sequence information; 4 isolates were not typeable.
‡One isolate was characterized after PCR amplification and sequencing as previously described (12).
§A total of 92 strains had toxins, but the total number of toxin genes detected was 93 because 1 isolate contained PVL and TSST-1.

Main Article

1These authors contributed equally to this article.

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