TY - JOUR AU - Cattoir, Vincent AU - Poirel, Laurent AU - Aubert, Camille AU - Soussy, Claude-James AU - Nordmann, Patrice T1 - Unexpected Occurrence of Plasmid-Mediated Quinolone Resistance Determinants in Environmental Aeromonas spp. T2 - Emerging Infectious Disease journal PY - 2008 VL - 14 IS - 2 SP - 231 SN - 1080-6059 AB - We searched for plasmid-mediated quinolone resistance determinants of the Qnr type in several water samples collected at diverse locations from the Seine River (Paris, France). The qnrS2 genes were identified from Aeromonas punctata subsp. punctata and A. media. The qnrS2 gene was located on IncU-type plasmids in both isolates, which resulted in increased MIC values of quinolones and fluoroquinolones, once they were transferred into Escherichia coli. The qnrS2 gene identified in A. punctata was part of novel genetic structure corresponding to a mobile insertion cassette element. This identification of plasmid-mediated qnr genes outside Enterobacteriaceae underlines a possible diffusion of those resistance determinants within gram-negative rods. KW - Qnr KW - QnrS KW - antibiotic resistance KW - reservoir KW - Aeromonas punctata subsp. punctata KW - Aeromonas media KW - mobile insertion cassette KW - research KW - France DO - 10.3201/eid1402.070677 UR - https://wwwnc.cdc.gov/eid/article/14/2/07-0677_article ER - End of Reference