TY - JOUR AU - Mbulaiteye, Sam M. AU - Pfeiffer, Ruth M. AU - Dolan, Bryan AU - Tsang, Victor C.W. AU - Noh, John AU - Mikhail, Nabiel N.H. AU - Abdel-Hamid, Mohamed AU - Hashem, Mohamed AU - Whitby, Denise AU - Strickland, G. Thomas AU - Goedert, James J. T1 - Seroprevalence and Risk Factors for Human Herpesvirus 8 Infection, Rural Egypt T2 - Emerging Infectious Disease journal PY - 2008 VL - 14 IS - 4 SP - 586 SN - 1080-6059 AB - To determine whether human herpesvirus 8 (HHV-8) is associated with schistosomal and hepatitis C virus infections in Egypt, we surveyed 965 rural household participants who had been tested for HHV-8 and schistosomal infection (seroprevalence 14.2% and 68.6%, respectively, among those <15 years of age, and 24.2% and 72.8%, respectively, among those ≥15 years of age). Among adults, HHV-8 seropositivity was associated with higher age, lower education, dental treatment, tattoos, >10 lifetime injections, and hepatitis C virus seropositivity. In adjusted analyses, HHV-8 seropositivity was associated with dental treatment among men (odds ratio [OR] 2.4, 95% confidence interval [CI] 1.1–5.2) and hepatitis C virus seropositivity among women (OR 3.3, 95% CI 1.4–7.9). HHV-8 association with antischistosomal antibodies was not significant for men (OR 2.1, 95% CI 0.3–16.4), but marginal for women (OR 1.5, 95% CI 1.0–2.5). Our findings suggest salivary and possible nosocomial HHV-8 transmission in rural Egypt. KW - HHV-8 KW - epidemiology KW - transmission KW - Africa KW - cancer KW - schistosomiasis KW - research KW - Egypt DO - 10.3201/eid1404.070935 UR - https://wwwnc.cdc.gov/eid/article/14/4/07-0935_article ER - End of Reference