TY - JOUR AU - Carney, Ryan M. AU - Husted, Stan AU - Jean, Cynthia AU - Glaser, Carol AU - Kramer, Vicki T1 - Efficacy of Aerial Spraying of Mosquito Adulticide in Reducing Incidence of West Nile Virus, California, 2005 T2 - Emerging Infectious Disease journal PY - 2008 VL - 14 IS - 5 SP - 747 SN - 1080-6059 AB - Epidemic transmission of West Nile virus (WNV) in Sacramento County, California, in 2005 prompted aerial application of pyrethrin, a mosquito adulticide, over a large urban area. Statistical analyses of geographic information system datasets indicated that adulticiding reduced the number of human WNV cases within 2 treated areas compared with the untreated area of the county. When we adjusted for maximum incubation period of the virus from infection to onset of symptoms, no new cases were reported in either of the treated areas after adulticiding; 18 new cases were reported in the untreated area of Sacramento County during this time. Results indicated that the odds of infection after spraying were ≈6× higher in the untreated area than in treated areas, and that the treatments successfully disrupted the WNV transmission cycle. Our results provide direct evidence that aerial mosquito adulticiding is effective in reducing human illness and potential death from WNV infection. KW - Arboviruses KW - California KW - geographic information systems KW - humans KW - insect vectors KW - insecticides KW - mosquito control KW - mosquitoes KW - pesticides KW - West Nile virus KW - research KW - United States DO - 10.3201/eid1405.071347 UR - https://wwwnc.cdc.gov/eid/article/14/5/07-1347_article ER - End of Reference