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Volume 14, Number 7—July 2008

Research

Testing for Coccidioidomycosis among Patients with Community-Acquired Pneumonia

Douglas C. Chang*Comments to Author , Shoana Anderson†, Kathleen Wannemuehler*, David M. Engelthaler†, Laura Erhart†, Rebecca H. Sunenshine†, Lauren A. Burwell*, and Benjamin J. Park*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Arizona Department of Health Services, Phoenix, Arizona, USA;

Main Article

Table 3

Characteristics of patients with community-acquired pneumonia (CAP) who were tested for coccidioidomycosis, Maricopa County, Arizona, January 2003–December 2004*

Characteristic Case-patients, no. (%), n = 60 Controls, no. (%), n = 76 Odds ratio (95% CI) Adjusted odds ratio† (95% CI)
Age >18 y 53 (88) 44 (58) 5.5 (2.1–15.3)‡ 5.3 (1.5–24.0)
Male 28 (55) 40 (53) 0.9 (0.5–1.9) NS
Chest pain 19 (32) 7 (9) 4.6 (1.8–11.8)‡ 3.9 (1.2–13.8)
Rash 5 (8) 0 Undefined (1.2–Undefined)‡ 21.1§ (2.2–undefined)
Diabetes mellitus or immunosuppressive condition 10 (17) 4 (5) 3.6 (1.0–16.5)‡ NS
Symptoms >14 d 20 (33) 6 (8) 5.8 (2.1–15.7)‡ 4.1 (1.3–14.2)

*CI, confidence interval; NS, not significant. Case-patients were patients who had CAP and had received Coccidioides spp. serologic testing, regardless of test result; controls were patients who had CAP but had not received Coccidioides spp. serologic testing.
†Adjusted odds ratios and exact 95%CI from a multivariable logistic regression model.
‡Significant (p<0.05) according to univariate analysis.
§Median unbiased estimate of the adjusted odds ratio.

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