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Volume 14, Number 8—August 2008

Research

Puumala Hantavirus Excretion Kinetics in Bank Voles (Myodes glareolus)

Jonas Hardestam*†1Comments to Author , Malin Karlsson*1, Kerstin I. Falk*†, Gert Olsson*‡§, Jonas Klingström*†, and Åke Lundkvist*†
Author affiliations: *Swedish Institute for Infectious Disease Control, Solna, Sweden; †Karolinska Institutet, Stockholm, Sweden; ‡Swedish Defence Research Agency, Umeå, Sweden; §Swedish University of Agricultural Sciences, Umeå;

Main Article

Table 2

Infection of bank voles with PUUV after intranasal inoculation with saliva, urine, and feces samples*

InoculumBank vole no.Seropositivity
PUUV RNA in excreta by time, d†
Day 21 PIDay 42 PISalivaUrineFeces
Saliva
1+NTNTNT
2NTNTNT
3NTNTNT
4
+
+

0, 6, 14, 19, 26, 35, 42
0, 19, 26, 42
0, 6, 14, 19, 26, 35, 42
Urine
5+NT0, 24, 26, 28NT
6NTNTNT
7+0, 6, 14, 19, 26, 35, 420, 14, 19, 350, 6, 14, 19, 26, 35, 42
8NTNTNT
9



NT
NT
NT
Feces10+NT6, 14, 24, 26, 35, 42NT
11NTNTNT
12+NT0, 24NT
13+0, 14, 19, 26, 35, 426, 19, 240, 6, 19, 26, 35, 42
14NTNTNT

*PUUV, Puumala virus; PI, postinfection; –, negative; +, positive; NT, not tested.
†Numbers indicate days PI for tested excretions. Days with positive excretions are shown in boldface.

Main Article

1These authors contributed equally to this article.

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