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Volume 14, Number 8—August 2008

Research

Genetic and Serologic Properties of Zika Virus Associated with an Epidemic, Yap State, Micronesia, 2007

Robert S. Lanciotti*Comments to Author , Olga L. Kosoy*, Janeen J. Laven*, Jason O. Velez*, Amy J. Lambert*, Alison J. Johnson*, Stephanie M. Stanfield*, and Mark R. Duffy*
Author affiliations: *Centers for Disease Control and Prevention, Fort Collins, Colorado, USA;

Main Article

Table 1

IgG and IgM testing with heterologous flaviviruses of patients infected with ZIKV, Yap State, Micronesia, 2007*

PatientDays after onset IgG
IgM
ZIKVZIKVDENVYFVJEVMVEVWNV
Primary flavivirus ZIKV
822a51.523.21.31.41.71.1
822b101.239.51.21.02.41.2
822c243.313.12.70.631.81.3
830a21.11.34.40.484.42.9
830b211.816.31.90.631.31.6
849a31.54.50.920.951.20.66
849b183.018.22.21.02.71.5
862a61.925.41.71.11.81.0
862b
20
2.6

15.4
2
1.1
2.3
1.1
Eq
Secondary flavivirus ZIKV (probable)
817a15.91.41.70.81.70.7
817b195.78.15.12.11.71.0
833a13.41.73.71.02.81.3
833b198.23.12.30.92.51.3
844a23.83.86.82.021.50.7
844b168.512.714.97.042.91.6
955a15.01.83.71.03.42.4Eq
955b1426.610.93.40.81.74.0Eq
968a14.01.71.30.61.21.2
968b312.320.42.90.80.92.0
839a310.923.40.72.72.1
839b204.917.22.22.11.91.8
847a50.90.944.14.12.31.3
847b814.121.51.43.31.12.6

*Ig, immunoglobulin; ZIKV, Zika virus; DENV, dengue virus type 1–4 mixture; YFV, yellow fever virus; JEV, Japanese encephalitis virus; MVEV, Murray Valley encephalitis virus; WNV, West Nile virus; –, negative. Eq, result in equivocal range of the assay. IgG and IgM testing was conducted by ELISA except for WNV, which was tested by microsphere assay; ELISA values are patient optical densities divided by negative control optical densities; <2, negative; 2–3 equivocal; >3 positive.

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