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Volume 14, Number 8—August 2008

Research

Genetic and Serologic Properties of Zika Virus Associated with an Epidemic, Yap State, Micronesia, 2007

Robert S. Lanciotti*Comments to Author , Olga L. Kosoy*, Janeen J. Laven*, Jason O. Velez*, Amy J. Lambert*, Alison J. Johnson*, Stephanie M. Stanfield*, and Mark R. Duffy*
Author affiliations: *Centers for Disease Control and Prevention, Fort Collins, Colorado, USA;

Main Article

Table 2

Neutralization testing with heterologous flaviviruses of patients infected with ZIKV, Yap State, Micronesia, 2007*

PatientDays after onsetPRNT90 titer
ZIKVDENV1DENV2DENV3DENV4JEVYFVWNVSLEVMVEV
Primary flavivirus ZIKV
822a5320<10<10<10<10<10<10<10<10<10
822b102,56010101010<10<10<10<10<10
822c245,12010101010<10<10<10<10<10
830a2<10<10NT‡NTNTNTNTNTNTNT
830b212,560<10<10<10<10<10<10<10<10<10
849a3<10<10<10<10<10<10<10<10<10<10
849b1810,240<10<10<10<10<1020<10<10<10
862a6320<10<10<10<10<10<10<10<10<10
862b
20
2,560
10
10
<10
<10
<10
<10
<10
10
<10
Secondary flavivirus ZIKV (probable)
817a18080160320160<10<10<104040
817b1910,2402,56020,4805,1205,120203201601,280640
833a1160320804020<10<10<10<10<10
833b1981,92020,4805,1205,1201,280<10<1080320320
844a2201,280640320160<10<1052020
844b1610,24040,98010,2405,1201,2805<10160640640
955a1401,280640160320<10<10<102020
955b14163,84081,92020,48010,2405,12010<106402,5601,280
968a1803203208040<10<10<104020
968b310,240640640160160<10<10104020
839a3<10<1010<10<10<1040<10<10<10
839b2010,240403208080<10640408080
847a5<10<10<10<10<10<10640<10<10<10
847b82,5604032016040<101,28080320320

*PRNT90 titer, 90% plaque-reduction neutralization test titer; ZIKV, Zika virus; DENV, dengue virus; JEV, Japanese encephalitis virus; YFV, yellow fever virus; WNV, West Nile virus; SLEV, St. Louis encephalitis virus; MVEV, Murray Valley encephalitis virus; NT, not tested (sample depleted).

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