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Volume 14, Number 9—September 2008

Research

Pediatric Parapneumonic Empyema, Spain

Ignacio ObandoComments to Author , Carmen Muñoz-Almagro, Luis A. Arroyo, David Tarrago, David Sanchez-Tatay, David Moreno-Perez, Sahar S. Dhillon, Cristina Esteva, Susanna Hernandez-Bou, Juan J. Garcia-Garcia, William P. Hausdorff, and Angela B. Brueggemann
Author affiliations: Virgen del Rocio Children’s Hospital, Seville, Spain (I. Obando, L.A. Arroyo, D. Sanchez-Tatay); Sant Joan de Deu Hospital, Barcelona, Spain (C. Muñoz-Almagro, C. Esteva, S. Hernandez-Bou, J.J. Garcia-Garcia); Spanish Reference Laboratory for Pneumococci, Madrid, Spain (D. Tarrago); Carlos de Haya Children’s Hospital, Malaga, Spain (D. Moreno-Perez); University of Oxford, Oxford, UK (S.S. Dhillon, A.B. Brueggemann);; GlaxoSmithKline Biologicals, Rixensart, Belgium (W.P. Hausdorff);

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Table 2

Pneumococcal serotypes identified among pleural fluid samples

Serotype* Barcelona, no. (%), n = 56 Seville/Malaga, no. (%), n = 55 Total no. (%), n = 111 p value
1 27 (48) 26 (47) 53 (48) 0.92
7F 3 (5) 11 (20) 14 (13) 0.02
3 5 (9) 7 (13) 12 (11) 0.56
5 6 (11) 3 (5) 9 (8) 0.28
14 4 (7) 5 (9) 9 (8) 0.74
19A 6 (11) 2 (4) 8 (7) 0.27
9V 2 (4) 0 2 (2) 0.50
6A 2 (4) 0 2 (2) 0.50
8 0 1 (2) 1 (0.9) 1
19F 1 (2) 0 1 (0.9) 1

*7-valent pneumococcal conjugate vaccine serotypes include 4, 6B, 9V, 14, 18C, 19F, 23F. Pleural fluid samples were collected in Barcelona from October 1, 2003, through June 30, 2006, and in Seville and Malaga from January 1, 2005, through June 20, 2006. Serotypes were determined by Quellung reaction or PCR testing or predicted based on complete multilocus sequence typing, as described in the text. Boldface represents a statistically significant result.

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