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Volume 15, Number 1—January 2009

Letter

Clostridium difficile–related Hospitalizations among US Adults, 2006

Marya D. ZilberbergComments to Author 
Author affiliation: University of Massachusetts, Amherst, Massachusetts, USA; EviMed Research Group, LLC, Goshen, Massachusetts, USA

Main Article

Table

Incidence of Clostridium difficile–related hospitalizations among US adults, 2000–2006, by age group and region*

Hospitalization variable Year
2000 2001 2002 2003 2004 2005 2006
All US adults per 10,000 population
18–44 y 1.31 1.33 1.66 1.71 1.96 2.26 2.39
45–64 y 4.53 4.58 5.92 6.31 7.20 8.48 9.09
65–84 y 22.41 23.94 31.61 33.74 39.06 46.57 48.96
>85 y
52.09
57.03
70.15
74.99
89.39
110.71
111.70
Principal diagnosis CDAD as a proportion of total CDAD, %
18–44 y 26.3 26.8 26.9 26.1 28.1 29.1 30.7
45–64 y 24.4 25.2 24.4 23.2 24.3 25.5 27.4
65–84 y 22.8 23.7 23.3 22.8 23.8 24.9 27.8
>85 y
22.1
24.4
23.6
23.2
24.0
25.0
29.8
By sex per 10,000 population
M 4.10 6.30 5.71 6.03 7.03 8.59 9.00
F
5.72
6.83
7.71
8.32
9.71
11.72
12.29
By sex per 1,000 hospitalizations
M 3.83 5.81 5.24 5.54 6.43 7.79 8.13
F
3.81
4.51
5.04
5.45
6.36
7.66
8.02
Regionally per 10,000 population
Northeast 7.05 7.59 9.30 10.40 10.73 14.46 14.28
Midwest 5.70 5.32 7.96 8.51 9.86 11.32 12.27
South 4.05 4.98 6.26 6.49 8.19 9.50 9.64
West
3.72
3.52
4.10
4.39
5.39
6.73
7.32
Regionally per 1,000 hospitalizations
Northeast 5.15 5.52 6.74 7.47 7.64 10.17 10.00
Midwest 4.36 3.98 5.90 6.31 7.26 8.26 8.97
South 2.97 3.59 4.49 4.66 5.89 6.83 7.06
West 3.41 3.24 3.76 4.00 4.92 6.16 6.85

*CDAD, C. difficile–associated disease.

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