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Volume 15, Number 1—January 2009

CME ACTIVITY

Sphingomonas paucimobilis Bloodstream Infections Associated with Contaminated Intravenous Fentanyl1

Lisa L. MaragakisComments to Author , Romanee Chaiwarith, Arjun Srinivasan, Francesca J. Torriani, Edina Avdic, Andrew Lee, Tracy R. Ross, Karen C. Carroll2, and Trish M. Perl2
Author affiliations: Johns Hopkins University School of Medicine, Baltimore, Maryland, USA (L.L. Maragakis, A. Lee, K.C. Carroll, T.M. Perl); Johns Hopkins University Bloomberg School of Public Health, Baltimore (R. Chaiwarith); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A. Srinivasan); University of California, San Diego, California, USA (F.J. Torriani); The Johns Hopkins Hospital, Baltimore (E. Avdic, T.R. Ross)

Main Article

Figure 2

Results of pulsed-field gel electrophoresis (PFGE) of Sphingomonas paucimobilis isolates obtained in November 2007. Lanes 1 and 10, molecular weight marker; lanes 2–7, bloodstream isolates from patients 1–6, respectively; lane 8, isolate from contaminated fentanyl; lane 9, unrelated control isolate. Patients 2 through 6 received intravenous fentanyl within 48 hours before S. paucimobilis bacteremia developed and had isolates with a PFGE pattern indistinguishable from that of fentanyl isolates. P

Figure 2. . . Results of pulsed-field gel electrophoresis (PFGE) of Sphingomonas paucimobilis isolates obtained in November 2007. Lanes 1 and 10, molecular weight marker; lanes 2–7, bloodstream isolates from patients 1–6, respectively; lane 8, isolate from contaminated fentanyl; lane 9, unrelated control isolate. Patients 2 through 6 received intravenous fentanyl within 48 hours before S. paucimobilis bacteremia developed and had isolates with a PFGE pattern indistinguishable from that of fentanyl isolates. Patient 1 did not receive intravenous fentanyl and had S. paucimobilis bacteremia with a distinct PFGE pattern.

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1Data presented in part at the 18th Annual Meeting of the Society for Healthcare Epidemiology of America; Orlando, Florida; April 6, 2008 (abstract 478).

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