Emerging Infectious Disease ISSN: 1080-6059

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Sphingomonas paucimobilis Bloodstream Infections Associated with Contaminated Intravenous Fentanyl¹

Lisa L. Maragakis

, Romanee Chaiwarith, Arjun Srinivasan, Francesca J. Torriani, Edina Avdic, Andrew Lee, Tracy R. Ross, Karen C. Carroll², and Trish M. Perl²

Author affiliations: Johns Hopkins University School of Medicine, Baltimore, Maryland, USA (L.L. Maragakis, A. Lee, K.C. Carroll, T.M. Perl); Johns Hopkins University Bloomberg School of Public Health, Baltimore (R. Chaiwarith); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A. Srinivasan); University of California, San Diego, California, USA (F.J. Torriani); The Johns Hopkins Hospital, Baltimore (E. Avdic, T.R. Ross)

Main Article

Table 1

Recently published reports of infectious outbreaks associated with contaminated medications prepared at compounding pharmacies, United States, 2002–2007

Reference	Organism	Infection ( no. patients)	Mode of transmission	Location of outbreak
(3)	Serratia marcescens	Bloodstream infections (18)	Intravenous magnesium sulfate	California, New Jersey, North Carolina, New York, Massachusetts
(4)	S. marcescens	Meningitis, epidural abscess, or joint infection (11)*	Epidural or intra-articular injection of betamethasone	California
(6)	Burkholderia cepacia	Bloodstream infections and sepsis (2 pediatric patients)	Intravenous antibiotic-lock flush solution	Connecticut
(7)	Hepatitis C	Acute hepatitis C (16)	Injected radiopharmaceutical for myocardial perfusion study	3 clinics in Maryland
(8,10)	Pseudomonas fluorescens	Bloodstream infections (64)	Heparin/saline intravenous flush	Missouri, New York, Texas, Michigan, South Dakota
(9)	Exophiala dermatitidis	Meningitis (5)†	Epidural injection of methylprednisolone‡	2 pain management clinics in North Carolina

*3 case-patients died.
†1 case-patient died.
‡Prepared by a compounding pharmacy in South Carolina and supplied to hospitals and clinics in 5 states.

Main Article

¹Data presented in part at the 18th Annual Meeting of the Society for Healthcare Epidemiology of America; Orlando, Florida; April 6, 2008 (abstract 478).

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