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Volume 15, Number 12—December 2009

Dispatch

Outbreak of Antiviral Drug–Resistant Influenza A in Long-Term Care Facility, Illinois, USA, 2008

Nila J. Dharan1, Monica Patton1, Alicia M. Siston2, Julie Morita, Enrique Ramirez, Teresa R. Wallis, Varough Deyde, Larisa V. Gubareva, Alexander I. Klimov, Joseph S. Bresee, and Alicia M. FryComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (N.J. Dharan, M. Patton, T.W. Wallis, V. Deyde, L.V. Gubareva, A.I. Klimov, J.S. Bresee, A.M. Fry); Chicago Department of Public Health, Chicago, Illinois, USA (A.M. Siston, J. Morita, E. Ramirez); 1Current affiliation: New York University School of Medicine, New York, New York, USA.; 2Current affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

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Table

Characteristics of 12 confirmed influenza case-patients in building A, long-term care facility, Illinois, USA, 2008*

Characteristic Influenza virus subtype
A (H1) (n = 9) A (H3) (n = 3)
Age, y, median (range)
29 (14–47)
32 (21–37)
Any underlying medical conditions 9 (100) 3 (100)
Neurologic disorders 9 (100) 3 (100)
Gastrointestinal disorders 8 (89) 3 (100)
Pulmonary disease
2 (22)
2 (67)
Fever >100.5°F
9 (100)
3 (100)
Cough
7 (78)
2 (67)
Desaturation 4 (44) 1 (33)
Lowest % oxygen saturation, median (range) 88.5 (88–92) 92 (NA)
Elevated or new oxygen requirement
2 (22)
0
Difficulty breathing
2 (22)
1 (33)
Increased secretions
3 (33)
2 (67)
Increased respiratory rate
3 (33)
0
Lethargy
1 (11)
0
Distress
3 (33)
0
Elevated level of care
4 (44)
1 (33)
Hospitalized† 1 (11) 0
Length of stay, d
1
NA
Clinical treatment
Antimicrobial drugs 3 (33) 0
Antipyretics 9 (100) 3 (100)
Nebulizer (albuterol)
3 (33)
1 (33)
Received 2007–08 influenza vaccine
8 (89)
3 (100)
Died‡ 1 (11) 0

*All values are no. (%) case-patients except as indicated. NA, not applicable.
†One case-patient was hospitalized for parotitis to rule out infection with mumps and was discharged in stable condition after 1 day.
‡One case-patient who had a diagnosis of end-stage lung disease and a do not resuscitate/do not intubate directive died.

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