Recombination in Vaccine and Circulating Strains of Porcine Reproductive and Respiratory Syndrome Viruses
Figure 2. Pathogenicity comparison among the Em2007, CH-1a, and WUH1 strains of porcine reproductive and respiratory syndrome virus (PRRSV). Forty-day-old piglets (9 piglets in each group) free of PRRSV were inoculated intramuscularly with 105.0 mean tissue culture infectious doses/2 mL of Em2007, CH-1a, WUH1, respectively. Two piglets from each group were euthanized and necropsied at 7 and 10 days postinoculation (dpi) for viral load analyses and histopathologic examinations. The remaining 5 piglets in each group were used to evaluate rate of death. Mean rectal temperature (A) and survival rate (B) of each group were recorded for 21 dpi.