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Volume 15, Number 3—March 2009

Research

Sources of Hepatitis E Virus Genotype 3 in the Netherlands

Saskia A. RutjesComments to Author , Willemijn J. Lodder, Froukje Lodder-Verschoor, Harold H.J.L. van den Berg, Harry Vennema, Erwin Duizer, Marion Koopmans, and Ana Maria de Roda Husman
Author affiliations: National Institute for Public Health and the Environment, Bilthoven, the Netherlands

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Figure 1

Maximum-parsimony tree of hepatitis E virus (HEV) sequences detected in pig, wild boar and water samples, based on a 148-nt sequence of open reading frame 2 (nt 6322–6469 of strain M73218). Sources of Dutch sequences and genotype 3 clusters are indicated. Sequences are compared with prototype sequences of different clusters of HEV genotype 3. Prototypes correspond with the following GenBank accession nos.: A) US1, AF060668; C) NLSW105, AF336298; E) UK-swine p354, AF503511; F) G1, AF110391. The f

Figure 1. Maximum-parsimony tree of hepatitis E virus (HEV) sequences detected in pig, wild boar and water samples, based on a 148-nt sequence of open reading frame 2 (nt 6322–6469 of strain M73218). Sources of Dutch sequences and genotype 3 clusters are indicated. Sequences are compared with prototype sequences of different clusters of HEV genotype 3. Prototypes correspond with the following GenBank accession nos.: A) US1, AF060668; C) NLSW105, AF336298; E) UK-swine p354, AF503511; F) G1, AF110391. The following accession numbers have been used for phylogenetic analysis of isolates from surface water: EU526620, EU526626, from wild boar; EU526642, from pig liver; DQ916142–DQ916144, from pig feces; and DQ996399, EU526606–EU526619, EU526621–EU526625, EU526627–EU526641, EU526643–EU526647.

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