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Volume 15, Number 4—April 2009
Research

Experimental Infection of Potential Reservoir Hosts with Venezuelan Equine Encephalitis Virus, Mexico

Eleanor R. Deardorff, Naomi L. Forrester, Amelia P. Travassos da Rosa, Jose G. Estrada-Franco, Roberto Navarro-Lopez, Robert B. Tesh, and Nikos VasilakisComments to Author 
Author affiliations: University of Texas Medical Branch, Galveston, Texas, USA (E.R. Deardorff, N.L. Forrester, A.P. Travassos da Rosa, J.G. Estrada-Franco, R.B. Tesh, S.C. Weaver); Comision Mexico–Estados Unidos para la Prevencion de la Fiebre Aftosa y Otras Enfermedades Exoticas de los Animales, Mexico City, Mexico (R. Navarro-Lopez)

Main Article

Table

Viremia in rodents that died 1–14 days after inoculation with 3.2 log10 PFU of Venezuelan equine encephalitis virus subtype IE strain MX01-22*

Rodent genus dpi† Tissue virus content (log10 PFU/g)†
Brain Heart Spleen Kidney Liver Lung
Oryzomys
2
1.8
2.7
3.3
2.0
3.2
0
Oligoryzomys 4 0 0 4.0 0 0 0

6
0
0
3.4
0
0
0
Baiomys 6 3.2 5.0 5.0 4.7 4.9 3.9
7 4.6 3.2 4.2 0 4.3 4.3
7 2.0 2.0 3.0 3.4 2.6 4.1
8 5.0 3.0 5.7 5.0 1.9 5.0

*Not shown are 3 Liomys salvini, 2 Oligoryzomys fulvescens, and 1 Sigmodon hispidus rodents. These animals died on days 5–10 postinoculation and showed no detectable virus in any organs tested. dpi, days postinoculation.
†Limit of detection was 1 plaque in150 μL homogenate. Tissue sample weight varied between 0.002 and 0.01 grams.

Main Article

Page created: December 10, 2010
Page updated: December 10, 2010
Page reviewed: December 10, 2010
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