Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 15, Number 4—April 2009
THEME ISSUE
The Amazon Region

Dispatches

Seroprevalence of Kaposi Sarcoma–associated Herpesvirus and Other Serologic Markers in the Brazilian Amazon

Maria C. NascimentoComments to Author , Laura M. Sumita, Vanda U. Souza, Helen A. Weiss, Juliane Oliveira, Melissa Mascheretti, Mariana Quiroga, Rodrigo A.R. Vela, Ester Sabino, Claudio S. Pannuti, and Philippe Mayaud
Author affiliations: Universidade de São Paulo, São Paulo, Brazil (M.C. Nascimento, L.M. Sumita, V.U. Souza, J. Oliveira, M. Mascheretti, M. Quiroga, R.A.R. Vela, E. Sabino, C.S. Pannuti); London School of Hygiene and Tropical Medicine, London, UK (M.C. Nascimento, H.A. Weiss, P. Mayaud)

Main Article

Table 1

Seroprevalence of KSHV among 3 populations in the Brazilian Amazon*†

Variables Mapuera Amerindians, n = 339†
Mapuera non-Amerindians, n = 181†
Manaus blood donors, n = 1,133†
% KSHV positive (no. tested) OR (95% CI) % KSHV positive (no. tested) OR (95% CI) % KSHV positive (no. tested) OR (95% CI)
Sex
Male 79.2 (144) 1 26.7 (75) 1 28.6 (874) 1
Female 82.6 (195) 1.2 (0.7–2.1) 27.4 (106) 1.0 (0.5–2.0) 34.4 (259) 1.3 (1.0–1.7)
p value

0.4


0.1


0.08
Age group, y
0–9 65.0 (43) 0.1 (0.05–0.4) 9.8 (51) 0.1 (0.03–0.3)
10–17 70.0 (93) 0.2 (0.07–0.4) 22.5 (40) 0.3 (0.1–0.7)
18–34 86.5 (104) 0.5 (0.2–1.3) 27.3 (44) 0.4 (0.1–0.9) 29.6 (916) 0.9 (0.7–1.3)
>35 92.9 (99) 1 50.0 (46) 1 31.3 (217) 1
p for trend

<0.001


<0.001



Crowding‡
1–2 93.7 (16) 1 55.6 (9) 1 32.6 (175) 1
3 91.3 (23) 0.7 (0.06–8.4) 33.3 (15) 0.4 (0.07–2.2) 29.9 (941) 0.9 (0.6–1.2)
>4 79.7 (300) 0.3 (0.03–2.0) 24.8 (145) 0.3 (0.07–1.3) 6.2 (16) 0.4 (0.2–1.0)
p value

0.1


0.1


0.1
Ethnicity
African 29.6 (743) 1
Caucasian 30.5 (308) 1.0 (0.8–1.4)
Indigenous 100 (339) 53.8 (13 2.8 (0.9–8.3)
Other 100 (181) 25.8 (66) 0.8 (0. 5–1.5)
p value







0.08
Hepatitis A virus
Negative 83.3 (6) 1 12.5 (16) 1 42.9 (7)§ 1
Positive 81.1 (333) 0.9 (0.1–7.5) 28.5 (165) 2.8 (0.6–12.7) 28.6 (154)§ 0.5 (0.1–2.5)
p value

0.9


0.2


0.4
Hepatitis B virus
Negative 81.6 (315) 1 32.0 (75)§ 1 30.2 (1,075) 1
Positive 73.9 (23) 0.6 (0.2–1.7) 53.3 (15)§ 2.4 (0.8–7.5) 25.0 (56) 0.8 (0.4–1.4)
p value

0.4


0.1


0.4
Hepatitis C virus
Negative 81.0 (338) 36.0 (90)† 29.9 (1,129) 1
Positive 0 0 25.0 (4) 0.8 (0.1–7.5)
p value







0.8
HSV-2
Negative 81.5 (314) 1 18.1 (127) 1 27.8 (715) 1
Positive 76.0 (25) 0.7 (0.3–1.9) 48.1 (54) 4.2 (2.1–8.5) 33.2 (406) 1.3 (1.0–1.7)
p value

0.5


<0.001


0.06
Trepomena pallidum
Negative 81.0 (338) 26.3 (171) 1 29.9 (1,122) 1
Positive 0 40.0 (10) 1.9 (0.5–6.9) 36.4 (11) 1.2 (0.6–2.3)
p value 0.3 0.7

*Seroreactivity by any serologic assay, whole virus. KSHV, Kaposi sarcoma–associated herpesvirus; OR, odds ratio; CI, confidence interval; HSV-2, herpes simplex virus type 2.
†Some figures do not add up to the total because of missing data.
‡Number of residents living in the house.
§Only a random subsample tested.

Main Article

TOP