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Volume 15, Number 5—May 2009

Research

New Respiratory Enterovirus and Recombinant Rhinoviruses among Circulating Picornaviruses

Caroline Tapparel1Comments to Author , Thomas Junier1, Daniel Gerlach, Sandra Van Belle, Lara Turin, Samuel Cordey, Kathrin Mühlemann, Nicolas Regamey, John-David Aubert, Paola M. Soccal, Philippe Eigenmann, Evgeny Zdobnov1, and Laurent Kaiser1
Author affiliations: University of Geneva Hospitals, Geneva, Switzerland (C. Tapparel, S. Van Belle, L. Turin, S. Cordey, P. M. Soccal, P. Eigenmann, L. Kaiser); University of Geneva Medical School, Geneva (C. Tapparel, T. Junier, D. Gerlach, S. Van Belle, L. Turin, S. Cordey, E. Zdobnov, L. Kaiser); Swiss Institute of Bioinformatics, Geneva (T. Junier, D. Gerlach, E. Zdobnov); University Hospital of Bern, Bern, Switzerland (K. Mühlemann, N. Regamey); University Hospital of Lausanne, Lausanne, Switzerland (J.-D. Aubert); Imperial College London, London, UK (E. Zdobnov); 1These authors contributed equally to this article.

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Figure 3

Nearest-neighbor relatedness of rhinovirus CL-013775 (and CL-073908) along the 5′ untranslated region/VP4/VP2 region (A), and nearest-neighbor relatedness of rhinovirus CL-135587 along the complete genome (B), identified by bootscanning. At each position of a sliding window, the solid circles indicate the closest relative within a defined threshold of the phylogenetic distance to CL-013775 (A) and CL-135587 (B). Both panels show phylogenetic trees of analyzed serotypes over the entire scanned re

Figure 3. Nearest-neighbor relatedness of rhinovirus CL-013775 (and CL-073908) along the 5′ untranslated region/VP4/VP2 region (A), and nearest-neighbor relatedness of rhinovirus CL-135587 along the complete genome (B), identified by bootscanning. At each position of a sliding window, the solid circles indicate the closest relative within a defined threshold of the phylogenetic distance to CL-013775 (A) and CL-135587 (B). Both panels show phylogenetic trees of analyzed serotypes over the entire scanned region. Human rhinovirus 7 (HRV-7), -9, -10, -11, -24, -32 (accession nos. EU096019, AF343584), -36, -39, -44, -56, -58 (EU096045, AY040236), -59, -67 (EU096054, AF343603, and DQ473505), -76, -88, and -89 sequences were obtained from GenBank (see Technical Appendix 2 Figure 1, for full-length genome accession numbers).

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