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Volume 15, Number 5—May 2009

Letter

Chikungunya Outbreak, Singapore, 2008

Yee S. LeoComments to Author , Angela L.P. Chow, Li Kiang TanComments to Author , David C. Lye, Li Lin, and Lee C. Ng
Author affiliations: Tan Tock Seng Hospital, Singapore (Y.S. Leo, A.L.P. Chow, D.C. Lye, L. Lin); National Environment Agency, Singapore (L.K. Tan, L.C. Ng); References

Main Article

Table

Daily trend of fever and viremia in 10 hospitalized chikungunya patients, Singapore (www.cdc.gov/EID/content/15/5/836-T.htm)

Patient no. Signs and symptoms* Fever† and chikungunya test results (viral load‡), by day of fever
–1 0 1 2 3 4 5 6 7 8 9 10
1 F, A, B, D NA 
+ 
(442.7) 37.7§
+ 
(3.5) 37.0
– 37.0
–
2 F, A, H, RE NA
+ 
(5,191.4) 39.6§
+ (3,655.2) 38.4
+ 
(119.1) 38.0 
+ 
(1.3) 37.6
– 38.5 38.0 37.4
3 F, A, R, H NA
+ 
(155.5) 39.3§
+ 
(385.2) 37.0
+
(3.7) 37.2
+
(0.4) 37.3
– 37.2
–
4 F, A NA
+ 
(0.8) 40.8§
+ (14,605.3) 39.9
+
(14,170.2) 38.2 
+ (1,007.8) 37.6
+
(4.0) 37.6
+
(0.2) 37.4
– 37.0
5 F, A NA 
+ 
(371.4) 37.0§
+
(25.9) 37.8
+ 
(0.4) 36.8
– 36.6
–
6 F, D, R, M NA
+ 
(524.4) 37.6§
+
(0.7) 38.6 
+ 
(0.4) 37.2
– 36.8
–
7 F, A, H, EP NA
+ 
(18.8) 38.3§
+
(7.2) 37.0 
+ 
(0.4) 37.0
–
8 F, A NA
+ (36.6) 37.5§ 37.6
+ 
(0.3) 37.7
– 36.4
9 F, A, N NA
+
(406.7) 38.4§
– 37.8 37.1 37.1
10 F, A, M 39.2§ 36.7 
+ 
(8.5) 36.8
+ 
(3.6) 37.1
– 37.4
– 36.8

*At hospitalization. F, fever; A, arthralgia; B, backache; D, diarrhea; H, headache; RE, red eyes; R, rash; M, myalgia; EP, eye pain; N, nausea.
†Day 0, day of fever onset. Maximum temperature expressed in ºC. Light shading indicates self-reported fever; dark shading indicates documented fever (maximum temperature >37.5 ºC). NA, not available.
‡Viral load expressed as × 103 pfu/mL. Reverse transcription–PCR test results for chikungunya: +, positive; –, negative.
§Indicates day patient was hospitalized.

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