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Volume 15, Number 7—July 2009
Research

Clusters of Multidrug-Resistant Mycobacterium tuberculosis Cases, Europe

Isabelle DevauxComments to Author , Kristin Kremer, Herre Heersma, and Dick van Soolingen
Author affiliations: European Centre for Disease Prevention and Control, Stockholm, Sweden (I. Devaux); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (K. Kremer, H. Heersma, D. Van Soolingen)

Main Article

Table 4

Predictors for clustered MDR TB strains compared with unique strains among 521 cases reported in 16 European countries, January 2003 through June 2007*

Variable MDR TB strains
Unadjusted OR (95% CI) Adjusted† OR (95% CI)
No. patients % Clustered
Sex
Male 347 48 1 1
Female
170
49
1.0 (0.7–1.5)
1.1 (0.6–1.9)
Age
15–44 324 43 1 1
45–64 143 61 2.1 (1.4–3.1) 1.3 (0.7–2.3)
>65
36
53
1.5 (0.7–3.0)
2.8 (0.8–9.4)
Origin
Baltic states 188 81 21.9 (10.6–44.9) 25.1 (9.9–64.0)
Other FSU countries‡ 99 61 7.7 (3.7–16.1) 8.7 (3.2–23.2)
Other European countries 72 17 1 1
Africa
71
24
1.6 (0.7–3.6)
1.1 (0.4–3.5)
Site of disease
Pulmonary 473 50 2.4 (1.2–4.9) 0.5 (0.2–1.6)
Extrapulmonary
41
29
1
1
Previous TB
Yes 163 54 1.0 (0.6–1.4) 1.1 (0.6–1.9)
No
248
55
1
1
XDR TB
Yes 51 82 4.1 (1.9–8.7) _
No 341 53 1

*TB, tuberculosis; MDR, multidrug-resistant; OR, odds ratio; CI, confidence interval; FSU, former Soviet Union; XDR, extensively drug-resistant. Boldface indicates significance.
†For all other factors in the model except XDR TB.
‡Former Soviet Union countries: Azerbaijan, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Ukraine, and Uzbekistan.

Main Article

Page created: November 08, 2010
Page updated: November 08, 2010
Page reviewed: November 08, 2010
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