Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 15, Number 7—July 2009

Research

Relapse Associated with Active Disease Caused by Beijing Strain of Mycobacterium tuberculosis1

William J. BurmanComments to Author , Erin E. Bliven, Lauren Cowan, Lorna Bozeman, Payam Nahid, Lois Diem, Andrew Vernon, and for the Tuberculosis Trials Consortium
Author affiliations: Denver Public Health, Denver Colorado, USA (W.J. Burman); University of Colorado at Denver Health Sciences Center, Denver (W.J. Burman); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (E.E. Bliven, L. Cowan, L. Bozeman, L. Diem, A. Vernon); The University of California, San Francisco, California, USA (P. Nahid)

Main Article

Table 3

Association between active disease caused by a Beijing genotype of Mycobacterium tuberculosis and relapse, adjusted for clinical risk factors, Tuberculosis Trials Consortium Study 22*

Characteristic Univariate analysis
Multivariate analysis
Odds ratio (95% CI) p value Odds ratio (95% CI) p value
Infected with Beijing genotype 2.0 (1.0–4.0) 0.05 2.2 (1.0–4.9) 0.07
Non-Hispanic white race/ethnicity 3.3 (1.7–6.1) <0.01 3.0 (1.4–6.7) <0.01
Underweight at tuberculosis diagnosis 4.7 (2.6–8.6) <0.01 3.7 (1.8–7.2) <0.01
Pulmonary cavitation 5.0 (2.4–10.7) <0.01 3.2 (1.4–7.5) 0.01
Bilateral pulmonary disease 2.9 (1.5–5.7) <0.01 1.8 (0.9–4.0) 0.12
Two-month sputum culture positivity 4.7 (2.6–8.7) <0.01 2.4 (1.2–4.9) 0.01

*The Tuberculosis Trials Consortium Study enrolled patients during 1995–1998. Participants in the case–control study were selected from among 1,004 HIV-infected participants. CI, confidence interval.

Main Article

1This study was presented in part at the 2008 International Conference of the American Thoracic Society, May 16–21, 2008, Toronto, Ontario, Canada.

TOP