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Volume 15, Number 7—July 2009

Research

Relapse Associated with Active Disease Caused by Beijing Strain of Mycobacterium tuberculosis1

William J. BurmanComments to Author , Erin E. Bliven, Lauren Cowan, Lorna Bozeman, Payam Nahid, Lois Diem, Andrew Vernon, and for the Tuberculosis Trials Consortium
Author affiliations: Denver Public Health, Denver Colorado, USA (W.J. Burman); University of Colorado at Denver Health Sciences Center, Denver (W.J. Burman); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (E.E. Bliven, L. Cowan, L. Bozeman, L. Diem, A. Vernon); The University of California, San Francisco, California, USA (P. Nahid)

Main Article

Table 5

Multivariate analyses of association between active disease caused by a Beijing strain of Mycobacterium tuberculosis and relapse among race/ethnicity groups while controlling for other risk factors for relapse, Tuberculosis Trials Consortium Study 22*

Characteristic Asian–Pacific Islander 
(n = 50)
Non-Hispanic black 
(n = 148)
Non-Hispanic white 
(n = 63)
Hispanic 
(n = 79)
OR (95% CI) p value OR (95% CI) p value OR (95% CI) p value OR (95% CI) p value
Infected with Beijing strain 15.8 (1.3–192) 0.03 1.8 (0.5–6.5) 0.35 1.0 (0.1–7.7) 0.98 1.0 (0.1–13) 0.97
Underweight at tuberculosis diagnosis 3.1 (0.3–34) 0.35 2.9 (0.8–6.3) 0.15 11 (2.4–48) <0.01 4.6 (0.9–24) 0.07
Pulmonary cavitation 2.1 (0.1–33) 0.60 4.0 (0.8–19) 0.09 2.7 (0.5–15) 0.25 6.6 (0.7–61) 0.09
Bilateral pulmonary disease 5.2 (0.4–69) 0.21 1.6 (0.5–4.8) 0.44 1.2 (0.2–9.9) 0.84 2.1 (0.3–15) 0.46
Two-month sputum culture positivity† 3.3 (1.1–9.7) 0.03 3.5 (0.6–20) 0.16 4.6 (0.5–40) 0.17

*The Tuberculosis Trials Consortium Study enrolled patients during 1995–1998. Participants in the case–control study were selected from among 1,004 HIV-infected participants. OR, odds ratio; CI, confidence interval.
†Not included for Asian–Pacific Islander patients because none were culture positive at 2 months.

Main Article

1This study was presented in part at the 2008 International Conference of the American Thoracic Society, May 16–21, 2008, Toronto, Ontario, Canada.

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