TY - JOUR AU - Valarcher, Jean-Francois AU - Knowles, Nick J. AU - Zakharov, Valery AU - Scherbakov, Alexey AU - Zhang, Zhidong AU - Shang, You-Jun AU - Liu, Zai-Xin AU - Liu, Xiang-Tao AU - Sanyal, Aniket AU - Hemadri, Divakar AU - Tosh, Chakradhar AU - Rasool, Thaha J. AU - Pattnaik, Bramhadev AU - Schumann, Kate R. AU - Beckham, Tammy R. AU - Linchongsubongkoch, Wilai AU - Ferris, Nigel P. AU - Roeder, Peter L. AU - Paton, David J. T1 - Multiple Origins of Foot-and-Mouth Disease Virus Serotype Asia 1 Outbreaks, 2003–2007 T2 - Emerging Infectious Disease journal PY - 2009 VL - 15 IS - 7 SP - 1046 SN - 1080-6059 AB - We investigated the molecular epidemiology of foot-and-mouth disease virus (FMDV) serotype Asia 1, which caused outbreaks of disease in Asia during 2003–2007. Since 2004, the region affected by outbreaks of this serotype has increased from disease-endemic countries in southern Asia (Afghanistan, India, Iran, Nepal, Pakistan) northward to encompass Kyrgyzstan, Tajikistan, Uzbekistan, several regions of the People’s Republic of China, Mongolia, Eastern Russia, and North Korea. Phylogenetic analysis of complete virus capsid protein 1 (VP1) gene sequences demonstrated that the FMDV isolates responsible for these outbreaks belonged to 6 groups within the Asia 1 serotype. Some contemporary strains were genetically closely related to isolates collected historically from the region as far back as 25 years ago. Our analyses also indicated that some viruses have spread large distances between countries in Asia within a short time. KW - Picornaviridae KW - Aphthovirus KW - foot-and-mouth disease virus KW - serotype Asia 1 KW - surveillance KW - epidemiology KW - phylogeny KW - sequencing data KW - viruses KW - research DO - 10.3201/eid1507.081621 UR - https://wwwnc.cdc.gov/eid/article/15/7/08-1621_article ER - End of Reference