Transgenic Mice Expressing Porcine Prion Protein Resistant to Classical Scrapie but Susceptible to Sheep Bovine Spongiform Encephalopathy and Atypical Scrapie
Figure 1. Electrophoretic profiles and antibody labeling of atypical proteinase K–resistant prion protein (PrPres) detected with monoclonal antibodies Sha31 (A) and 12B2 (B) in different isolates used for inoculating porcine PrP transgenic mice. Panels A and B were loaded with the same quantities of extracted PrPres from each sample. MW, molecular mass in kilodaltons.