Volume 15, Number 8—August 2009
National Outbreak of Acanthamoeba Keratitis Associated with Use of a Contact Lens Solution, United States
|Demographic characteristic or exposure†||No. (%) case-patients, n = 72||No. (%) controls, n = 140||Adjusted matched OR (95% CI)‡|
|AMOCMP||40 (55.6)||15 (10.7)||16.9 (4.8–59.5)|
|Ever top off or reuse old solution in case||40 (57.1)||30 (22.7)||2.8 (1.2–6.8)|
|<5 y as contact lens wearer||37 (51.4)||32 (22.9)||2.8 (1.0–7.6)|
*OR, odds ratio; CI, confidence interval; AMOCMP, Advanced Medical Optics Complete MoisturePlus.
†During 1mo before symptom onset. Missing values excluded from analysis.
‡Adjusted for age and sex. p<0.05.
1Other members of the Acanthamoeba Keratitis Investigation Team: Stephanie P. Johnston, Alexandre DaSilva, Yvonne Qvarnstrom, Rama R. Sriram, E. Danielle Rentz, Leslie B. Hausman, Shannon K. Cosgrove, Brandy L. Peterson, Nicholas P. DiMeo, Rebecca C. Greco-Kone, Angela J. Deokar, Susan Brim, Aaron S. Kusano, David E. Cheek, Sharlene Persaud, Felicia Chow (Centers for Disease Control and Prevention [CDC]); Ingrid Trevino, (CDC and Illinois Department of Public Health, Springfield, IL, USA); Gita G. Mirchandani (CDC and Maryland Department of Health and Mental Hygiene, Baltimore, MD, USA); Emily J. Luckman (Maryland Department of Health and Mental Hygiene); Stacy M. Holzbauer (CDC and Minnesota Department of Health, St. Paul, MN, USA); Zack Moore (CDC and North Carolina Department of Health and Human Services, Raleigh, NC, USA); Adam J. Langer, Mary T. Glenshaw (CDC and New Jersey Department of Health and Human Services, Trenton, NJ, USA); Michael Cooper (CDC and Ohio Department of Health, Columbus, OH, USA); Tai-Ho Chen (CDC and Pennsylvania Department of Health, Harrisburg, PA, USA); Kira A. Christian (CDC and South Carolina Department of Health and Environmental Control, Columbia, SC, USA); L. Rand Carpenter (CDC and Tennessee Department of Health, Nashville, TN, USA); Marion A. Kainer (Tennessee Department of Health); John R. Su (CDC and Texas Department of Health, Austin, TX, USA); Ami S. Patel (CDC and Virginia Department of Health, Richmond, VA, USA); Aron J. Hall (CDC and West Virginia Department of Health and Human Resources, Charleston, WV, USA); Charlotte E. Joslin (University of Illinois at Chicago); Kirk R. Wilhelmus (Baylor College of Medicine)
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