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Volume 15, Number 8—August 2009

Letter

Human Rhinovirus Group C in Hospitalized Children, Singapore

Boon-Huan TanComments to Author , Liat-Hui Loo, Elizabeth Ai-Sim Lim, Shirley Lay-Kheng Seah, Raymond T.P. Lin, Nancy W.S. Tee, and Richard J. Sugrue
Author affiliations: DSO National Laboratories, Singapore (B.-H. Tan, E.A.-S. Lim, S.L.-K. Seah); Nanyang Technological University, Singapore (L.-H. Loo, R.J. Sugrue); Kandang Kerbau Women’s and Children’s Hospital, Singapore (L.-H. Loo, N.W.S. Tee); National University Hospital, Singapore (R.T.P. Lin)

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Figure

Phylogenetic analysis of human rhinoviruses (HRVs) from Singapore based on nucleotide sequences of the 5′ noncoding region. The tree was constructed by using the neighbor-joining method with 1,000 bootstrapped replicates generated by MEGA version 4 software (9). Sequences (GenBank accession nos. FJ645828–FJ645771) of viruses from Singapore (SIN) are indicated, where the 2 numbers represent the year the specimen was collected, and NTU (Nanyang Technological University) followed by 3 numbers represents the specimen number. Representative strains of HRV-C are indicated by squares, HRV-B by circles, and HRV-A by triangles. RV indicates rhinovirus strains, followed by the serotype no. These sequences were obtained from the report by Lee et al. (3). Boldface indicates a cluster of 10 HRV-A strains that diverged from reference HRV-A strains. Scale bar indicates nucleotide substitutions per site.

Figure. Phylogenetic analysis of human rhinoviruses (HRVs) from Singapore based on nucleotide sequences of the 5′ noncoding region. The tree was constructed by using the neighbor-joining method with 1,000 bootstrapped replicates generated by MEGA version 4 software (9). Sequences (GenBank accession nos. FJ645828–FJ645771) of viruses from Singapore (SIN) are indicated, where the 2 numbers represent the year the specimen was collected, and NTU (Nanyang Technological University) followed by 3 numbers represents the specimen number. Representative strains of HRV-C are indicated by squares, HRV-B by circles, and HRV-A by triangles. RV indicates rhinovirus strains, followed by the serotype no. These sequences were obtained from the report by Lee et al. (3). Boldface indicates a cluster of 10 HRV-A strains that diverged from reference HRV-A strains. Scale bar indicates nucleotide substitutions per site.

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