TY - JOUR AU - Ayelet, Gelagay AU - Mahapatra, Mana AU - Gelaye, Esayas AU - Egziabher, Berhe G. AU - Rufeal, Tesfaye AU - Sahle, Mesfin AU - Ferris, Nigel P. AU - Wadsworth, Jemma AU - Hutchings, Geoffrey H. AU - Knowles, Nick J. T1 - Genetic Characterization of Foot-and-Mouth Disease Viruses, Ethiopia, 1981–2007 T2 - Emerging Infectious Disease journal PY - 2009 VL - 15 IS - 9 SP - 1409 SN - 1080-6059 AB - Foot-and-mouth disease (FMD) is endemic to sub-Saharan Africa. To further understand its complex epidemiology, which involves multiple virus serotypes and host species, we characterized the viruses recovered from FMD outbreaks in Ethiopia during 1981–2007. We detected 5 of the 7 FMDV serotypes (O, A, C, Southern African Territories [SAT] 1, and SAT 2). Serotype O predominated, followed by serotype A; type C was not recognized after 1983. Phylogenetic analysis of virus protein 1 sequences indicated emergence of a new topotype within serotype O, East Africa 4. In 2007, serotype SAT 1 was detected in Ethiopia and formed a new distinct topotype (IX), and serotype SAT 2 reappeared after an apparent gap of 16 years. The diversity of viruses highlights the role of this region as a reservoir for FMD virus, and their continuing emergence in Ethiopia will greatly affect spread and consequent control strategy of the disease on this continent. KW - FMD virus KW - serotype KW - phylogenetic tree KW - vaccine strain KW - Ethiopia KW - viruses KW - research DO - 10.3201/eid1509.090091 UR - https://wwwnc.cdc.gov/eid/article/15/9/09-0091_article ER - End of Reference