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Volume 15, Number 9—September 2009

Research

Predicting Phenotype and Emerging Strains among Chlamydia trachomatis Infections

Deborah DeanComments to Author , William J. Bruno, Raymond Wan, João P. Gomes, Stéphanie Devignot, Tigist Mehari, Henry J.C. de Vries, Servaas A. Morré, Garry Myers, Timothy D. Read, and Brian G. Spratt
Author affiliations: Children’s Hospital Oakland Research Institute, Oakland, California, USA (D. Dean, R. Wan, T. Mehari); University of California, San Francisco, California, USA (D. Dean); University of California, Berkeley, California, USA (D. Dean); Los Alamos National Laboratories, Los Alamos, New Mexico, USA (W.J. Bruno); National Institute of Health, Lisbon, Portugal (J.P. Gomes); Institut de Médecine Tropicale du Service de Santé des Armées, Marseille, France (S. Devignot); University of Amsterdam, the Netherlands (H.J.C. de Vries); Vrije Universiteit Medical Center, Amsterdam (S.A. Morré); University of Maryland School of Medicine, Baltimore, Maryland, USA (G. Myers); Emory University, Atlanta, Georgia, USA (T.D. Read); Imperial College, London, UK (B.G. Spratt)

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Figure 5

SplitsTree obtained by using concatenated sequences of the 7 loci for the 87 isolates. Cluster I, noninvasive, nonprevalent Chlamydia trachomatis strains (gold) with trachoma Subcluster I (red); cluster II, invasive lymphogranuloma venereum (LGV) isolates (purple); and cluster III, noninvasive globally prevalent sexually transmitted infection (STI) strains (blue). Isolates colored green represent putative recombinant strains. Scale bar indicates number of substitutions per site.

Figure 5. SplitsTree obtained by using concatenated sequences of the 7 loci for the 87 isolates. Cluster I, noninvasive, nonprevalent Chlamydia trachomatis strains (gold) with trachoma Subcluster I (red); cluster II, invasive lymphogranuloma venereum (LGV) isolates (purple); and cluster III, noninvasive globally prevalent sexually transmitted infection (STI) strains (blue). Isolates colored green represent putative recombinant strains. Scale bar indicates number of substitutions per site.

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