Artesunate Misuse and Plasmodium falciparum Malaria in Traveler Returning from Africa
Dea Shahinas, Rachel Lau, Krishna Khairnar, David Hancock, and Dylan R. Pillai
Author affiliations: Author affiliations: University of Toronto, Toronto, Ontario, Canada (D. Shahinas, K. Khairnar, D.R. Pillai); Ontario Agency for Health Protection and Promotion, Toronto (R. Lau, D.R. Pillai); Ajax-Pickering Hospital, Ajax, Ontario, Canada (D. Hancock)
Figure. In vitro drug susceptibility of representative patient isolates from returning travelers who visited friends and relatives in Africa. The mean 50% inhibitory concentrations (IC50) of chloroquine, mefloquine, artemisinin, artesunate, dihydroartemisinin, and artemether are plotted in nmol/L for each isolate, performed in triplicate (error bars indicate SD; n = 3). Nigeria A denotes the patient described in this report. The black horizontal line represents the median value.
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