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Volume 16, Number 10—October 2010

Dispatch

Artesunate Misuse and Plasmodium falciparum Malaria in Traveler Returning from Africa

Dea Shahinas, Rachel Lau, Krishna Khairnar, David Hancock, and Dylan R. PillaiComments to Author 
Author affiliations: Author affiliations: University of Toronto, Toronto, Ontario, Canada (D. Shahinas, K. Khairnar, D.R. Pillai); Ontario Agency for Health Protection and Promotion, Toronto (R. Lau, D.R. Pillai); Ajax-Pickering Hospital, Ajax, Ontario, Canada (D. Hancock)

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Figure

In vitro drug susceptibility of representative patient isolates from returning travelers who visited friends and relatives in Africa. The mean 50% inhibitory concentrations (IC50) of chloroquine, mefloquine, artemisinin, artesunate, dihydroartemisinin, and artemether are plotted in nmol/L for each isolate, performed in triplicate (error bars indicate SD; n = 3). Nigeria A denotes the patient described in this report. The black horizontal line represents the median value.

Figure. In vitro drug susceptibility of representative patient isolates from returning travelers who visited friends and relatives in Africa. The mean 50% inhibitory concentrations (IC50) of chloroquine, mefloquine, artemisinin, artesunate, dihydroartemisinin, and artemether are plotted in nmol/L for each isolate, performed in triplicate (error bars indicate SD; n = 3). Nigeria A denotes the patient described in this report. The black horizontal line represents the median value.

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