Volume 16, Number 10—October 2010
Research
Oral Fluid Testing during 10 Years of Rubella Elimination, England and Wales
Gayatri Manikkavasagan, Antoaneta Bukasa, Kevin E. Brown, Bernard J. Cohen, and Mary E. Ramsay
Table 3
Regional variation in rubella reports by oral (crevicular) fluid testing and confirmed cases from oral fluid and serum, England and Wales, 1999–2008
| Region | No. reported cases | Incidence of reported cases* | No. oral fluid tests (% total reports) | No. cases confirmed by oral fluid testing | No. cases confirmed by serum testing | Annual incidence of confirmed cases* |
||
|---|---|---|---|---|---|---|---|---|
| Confirmed by oral fluid testing† | Confirmed by serum testing | Total | ||||||
| East Midlands | 1,336 | 319 | 1,065 (80) | 3 | 9 | 0.09 | 0.21 | 0.29 |
| Eastern | 1,212 | 224 | 1,232 (102)‡ | 44 | 32 | 0.80 | 0.59 | 1.41 |
| London | 1,653 | 226 | 1,452 (88) | 32 | 67 | 0.67 | 0.92 | 1.35 |
| North East | 840 | 331 | 574 (68) | 0 | 12 | 0.00 | 0.47 | 0.47 |
| North West | 1,662 | 245 | 1,505 (91) | 12 | 13 | 0.25 | 0.19 | 0.37 |
| South East | 2,363 | 295 | 2,350 (99) | 18 | 48 | 0.34 | 0.60 | 0.82 |
| South West | 1,109 | 224 | 857 (77) | 13 | 40 | 0.31 | 0.81 | 1.07 |
| West Midlands | 1,235 | 234 | 821 (66) | 12 | 10 | 0.33 | 0.19 | 0.42 |
| Wales | 639 | 220 | 518 (81) | 1 | 10 | 0.02 | 0.34 | 0.38 |
| Yorkshire and Humberside | 1,903 | 382 | 1,260 (66) | 7 | 22 | 0.20 | 0.44 | 0.58 |
| Not specified |
75 |
1 |
0 |
|||||
| Total | 13,952 | 266 | 11,709 (84) | 143 | 263 | 0.31 | 0.50 | 0.77 |
*Incidence per 1 million population. Annual incidence calculated by using 2001 census population figures.
†Adjusted for proportion of cases tested.
‡Several oral fluid tests were conducted for cases that were not formally reported during university outbreaks in 3 regions in 1999, including the South West, Eastern, and North West regions (17).
