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Volume 16, Number 10—October 2010

Dispatch

Severe Plasmodium vivax Malaria, Brazilian Amazon

Márcia A. Alexandre, Cynthia O. Ferreira, André M. Siqueira, Belisa L. Magalhães, Maria Paula G. Mourão, Marcus V. LacerdaComments to Author , and Maria das Graças C. Alecrim
Author affiliations: Author affiliations: Fundação de Medicina Tropical do Amazonas, Manaus, Brazil (M.A. Alexandre, C.O. Ferreira, M.P.G. Mourão, M.V. Lacerda); Universidade do Estado do Amazonas, Manaus (M.A. Alexandre, A.M. Siqueira, B.L. Magalhães, M.P.G. Mourão, M.V. Lacerda, M.G.C. Alecrim); Centro Universitário Nilton Lins, Manaus (M.A. Alexandre, A.M. Siqueira, M.P.G. Mourão, M.V. Lacerda, M.G.C. Alecrim)

Main Article

Table 1

Clinical characteristics of 17 hospitalized patients who had parasitologic and molecular diagnosis of Plasmodium vivax infection, Manaus, Brazil, 2001–2002*

Patient no. Year Age/sex WHO severity criterion Duration of disease, d Antimicrobial drug use Erythrocyte transfusion Concurrent condition ICU Death
1 2001 2 y/F Severe anemia† 4 No Yes No No
2 2001 9 mo/M Severe anemia† 10 No Yes No No
3 2001 3 y/F Jaundice‡ 3 No No HAV No No
4 2001 60 y/F Acute renal failure§ 7 No No Arterial hypertension No No
5 2001 1 mo/M Severe anemia† 3 No Yes No No
6 2001 40 y/M Jaundice‡ 9 No No No No
7 2001 80 y/M Acute renal failure§ 6 No No No No
8 2002 7 y/M Hemoglobinuria/ jaundice‡ 4 No Yes No No
9 2002 5 mo/M Severe anemia†/
ARDS 3 No Yes No No
10 2002 28 d/M Jaundice‡ 5 No No No No
11 2002 46 y/F Severe anemia†/
ARDS 5 No Yes Yes Yes
12 2002 48 y/F Jaundice‡ 7 No No No No
13 2002 58 y/M Jaundice‡ 12 No No Diabetes No No
14 2002 47 y/F Jaundice‡ 8 No No No No
15 2002 43 y/F Shock¶/jaundice 4 Yes Yes Yes No
16 2002 34 y/M Jaundice 10 No No No No
17 2002 50 y/M Jaundice 7 No No No No

*WHO, World Health Organization; ICU, intensive care unit; HAV, hepatitis A virus; ARDS, acute respiratory distress syndrome (tachypnea, shortness of breath, and signs of hypoxemia).
†Hemoglobin <7 g/dL in adults and <5 g/dL in children.
‡Total bilirubin >3.0 mg/dL.
§Creatinine >3.0 mg/dL.
¶Systolic arterial tension <80 mm Hg despite fluid therapy.

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