Lymphotropism of Merkel Cell Polyomavirus Infection, Nova Scotia, Canada
Figure. Merkel cell polyomavirus (MCPyV) large T-antigen (T-ag) expression in human tissues. A) Merkel cell carcinoma stained with CM2B4 antibody as a positive control; MCPyV T-ag was detected. B) Expression of MCPyV T-ag in small lymphocytes in an MCPyV DNA–positive angioimmunoblastic T-cell lymphoma, stained with CM2B4. C) MCPyV DNA–positive reactive lymphoid hyperplasia sample reacted with CM2B4; no T-ag was detected. D) MCPyV DNA-negative chronic lymphocytic leukemia/small lymphocytic lymphoma sample stained with CM2B4; no T-ag was detected. Original magnification ×40.