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Volume 16, Number 11—November 2010

Research

Lymphotropism of Merkel Cell Polyomavirus Infection, Nova Scotia, Canada

Sonia Toracchio, Annette Foyle, Vojtech Sroller1, Jon A. Reed, Jun Wu, Claudia A. Kozinetz, and Janet S. ButelComments to Author 
Author affiliations: Baylor College of Medicine, Houston, Texas, USA (S. Toracchio, V. Sroller, J.A. Reed, C.A. Kozinez, J.S. Butel); Dalhousie University, Halifax, Nova Scotia, Canada (A. Foyle); Queen Elizabeth II Health Science Center, Halifax (A. Foyle); and Public Health Agency of Canada, Ottawa, Ontario, Canada (J. Wu); 1Current affiliation: Institute of Hematology and Blood Transfusion, Prague, Czech Republic

Main Article

Table 4

Presence of MCPyV in benign lymph nodes, lymph nodes with metastatic cancer, and other inflammatory or neoplastic tissues, Nova Scotia, Canada, 1994–2001*

Pathologic feature No. samples tested No. (%) MCPyV positive
Benign lymph nodes 110 11 (10)
Acute lymphadenitis 1 0
Atypical hyperplasia 2 0
Dermatopathic lymphadenopathy 3 0
Florid follicular hyperplasia 1 0
Mycobacterium avium–intracellulare infection 2 0
Necrotizing granulomas 3 0
Normal lymph node 29 3 (10.3)
Reactive hyperplasia 61 8 (13.1)
Sarcoidosis 6 0
Systemic mast cell disease 1 0
Toxoplasmosis
1
0
Lymph nodes with metastatic tumors 27 0
Carcinoma 25 0
Melanoma
2
0
Other inflammatory tissues 7 0
Chronic sialadenitis 1 0
Follicular bronchiolitis 1 0
Hemophagocytic syndrome, spleen 1 0
Helicobacter pylori–associated gastritis 1 0
Hemochromatosis, liver 1 0
Hyperplasia and chronic perifolliculitis, skin 1 0
Interstitial pneumonitis
1
0
Other neoplastic tissues 13 0
Mixed mullerian tumor 1 0
Neurofibroma 1 0
Sarcoma 4 0
Schwannoma 2 0
Thymoma 5 0

*MCPyV, Merkel cell polyomavirus.

Main Article

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