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Volume 16, Number 11—November 2010

Research

Genetic Structure of Plasmodium falciparum and Elimination of Malaria, Comoros Archipelago

Stanislas Rebaudet1, Hervé Bogreau1, Rahamatou Silaï, Jean-François Lepère, Lionel Bertaux, Bruno Pradines, Jean Delmont, Philippe Gautret, Philippe Parola, and Christophe RogierComments to Author 
Author affiliations: Institute for Biomedical Research of the French Army, Marseille, France (S. Rebaudet, H. Bogreau, L. Bertaux, B. Pradines, C. Rogier); Université de la Méditerranée, Marseille (J. Delmont, P. Parola); Assistance Publique–Hôpitaux de Marseille, Marseille (P. Gautret); Programme National de Lutte contre le Paludisme, Moroni, Comoros (R. Silaï); Dispensaire de Bandraboua, Mayotte, France (J.-F. Lepère); 1These authors contributed equally to this article.

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Figure 3

Relationship between geographic and genetic distances for each pair of Comoros islands (top) and between mean percentage of travelers among sampled patients and genetic distance for each pair of Comoros islands (bottom). Genetic distances were calculated as (FST/1 – FST ), where FST is the Wright F statistic. Mean percentage of travelers was calculated from the total number of sampled patients in one site (NA) with history of recent arrival from another site (NB) by using the equation ([NB→A/NA]

Figure 3. Relationship between geographic and genetic distances for each pair of Comoros islands (top) and between mean percentage of travelers among sampled patients and genetic distance for each pair of Comoros islands (bottom). Genetic distances were calculated as (FST/1 – FST ), where FST is the Wright F statistic. Mean percentage of travelers was calculated from the total number of sampled patients in one site (NA) with history of recent arrival from another site (NB) by using the equation ([NB→A/NA] + [NA→B/NB])/2; data in Table 1. GC, Grande Comore; MOH, Moheli; ANJ, Anjouan; MAY, Mayotte; Ln, logarithmically transformed.

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