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Volume 16, Number 11—November 2010

Research

Genetic Structure of Plasmodium falciparum and Elimination of Malaria, Comoros Archipelago

Stanislas Rebaudet1, Hervé Bogreau1, Rahamatou Silaï, Jean-François Lepère, Lionel Bertaux, Bruno Pradines, Jean Delmont, Philippe Gautret, Philippe Parola, and Christophe RogierComments to Author 
Author affiliations: Institute for Biomedical Research of the French Army, Marseille, France (S. Rebaudet, H. Bogreau, L. Bertaux, B. Pradines, C. Rogier); Université de la Méditerranée, Marseille (J. Delmont, P. Parola); Assistance Publique–Hôpitaux de Marseille, Marseille (P. Gautret); Programme National de Lutte contre le Paludisme, Moroni, Comoros (R. Silaï); Dispensaire de Bandraboua, Mayotte, France (J.-F. Lepère); 1These authors contributed equally to this article.

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Table 3

MOIs of Plasmodium falciparum infections for the 5 sites studied, Comoros archipelago and Marseille, France*

Locus Grande Comore
Moheli
Anjouan
Mayotte
Marseille
No. MOI No. MOI No. MOI No. MOI No. MOI
All 6 loci
36
1.39

36
1.47

36
2.11

36
1.22

36
1.64
Pf2689 34 1.03 27 1.07 36 1.19 36 1.08 36 1.22
7A11 34 1.12 32 1.19 35 1.37 36 1.14 36 1.39
C4M79 34 1.21 25 1.32 33 1.55 36 1.11 36 1.42
Pf2802 31 1.00 23 1.00 32 1.00 36 1.00 36 1.00
TRAP 35 1.42 29 1.14 36 1.67 36 1.08 36 1.19
C4M69
32
1.06

21
1.19

34
1.12

36
1.03

36
1.11
Mean no. alleles per locus 8.5 8 8.5 4.5 7.8

*Based on no. multi-infected isolates as shown in Table 2. MOI, multiplicity of infection (no. multi-infected isolates/no. randomly genotyped isolates); no., no. randomly genotyped isolates.

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