TY - JOUR AU - Esona, Mathew D. AU - Mijatovic-Rustempasic, Slavica AU - Conrardy, Christina AU - Tong, Suxiang AU - Kuzmin, Ivan V. AU - Agwanda, Bernard AU - Breiman, Robert F. AU - Banyai, Krisztian AU - Niezgoda, Michael AU - Rupprecht, Charles E. AU - Gentsch, Jon R. AU - Bowen, Michael D. T1 - Reassortant Group A Rotavirus from Straw-colored Fruit Bat (Eidolon helvum) T2 - Emerging Infectious Disease journal PY - 2010 VL - 16 IS - 12 SP - 1844 SN - 1080-6059 AB - Bats are known reservoirs of viral zoonoses. We report genetic characterization of a bat rotavirus (Bat/KE4852/07) detected in the feces of a straw-colored fruit bat (Eidolon helvum). Six bat rotavirus genes (viral protein [VP] 2, VP6, VP7, nonstructural protein [NSP] 2, NSP3, and NSP5) shared ancestry with other mammalian rotaviruses but were distantly related. The VP4 gene was nearly identical to that of human P[6] rotavirus strains, and the NSP4 gene was closely related to those of previously described mammalian rotaviruses, including human strains. Analysis of partial sequence of the VP1 gene indicated that it was distinct from cognate genes of other rotaviruses. No sequences were obtained for the VP3 and NSP1 genes of the bat rotavirus. This rotavirus was designated G25-P[6]-I15-R8(provisional)-C8-Mx-Ax-N8-T11-E2-H10. Results suggest that several reassortment events have occurred between human, animal, and bat rotaviruses. Several additional rotavirus strains were detected in bats. KW - Straw-colored fruit bat KW - Eidolon helvum KW - rotavirus KW - viruses KW - reassortment KW - heterologous genome segments KW - podcast KW - zoonoses KW - research KW - Kenya DO - 10.3201/eid1612.101089 UR - https://wwwnc.cdc.gov/eid/article/16/12/10-1089_article ER - End of Reference