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Volume 16, Number 2—February 2010

Research

Epidemiology of Cryptococcus gattii, British Columbia, Canada, 1999–2007

Eleni GalanisComments to Author , Laura MacDougall, Sarah Kidd, Mohammad Morshed, and the British Columbia Cryptococcus gattii Working Group
Author affiliations: British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada (E. Galanis, L. MacDougall); University of British Columbia, Vancouver (E. Galanis)

Main Article

Table 1

Characteristics of persons with cases of confirmed or probable Cryptococcus gattii infection, British Columbia, Canada, 1999–2007*

Characteristic Total Confirmed Probable p value
No. cases 218 124 94 NA
Average incidence (million/year) 5.8 3.3 2.5 NA
No. cases in persons living on Vancouver Island
161 (73.9)
83 (66.9)
78 (83.0)
0.177
Demographic data
Male sex 121 (55.5) 73 (58.9) 48 (51.1) 0.440
Age, y
Mean 58.7 58.7 58.7 0.988
Range 2–92 2–92 12–87 NA
Children <18 y
4 (1.8)
3 (2.4)
1 (1.1)
0.463
Clinical assessment
Respiratory syndrome 167 (76.6) 85 (68.5) 82 (87.2) 0.031
CNS syndrome 17 (7.8) 16 (12.9) 1 (1.1) 0.001
Respiratory and CNS syndrome 22 (10.1) 20 (16.1) 2 (2.1) <0.001
Other/unknown 12 (5.5) 3 (2.4) 9 (9.6) NA
Asymptomatic
16 (7.3)
6 (4.8)
10 (11.0)
0.120
Hospitalized 98 (60.9) 58 (65.2) 40 (55.6) 0.434
Immunocompromised 70 (38.0) 41 (38.7) 29 (37.2) 0.870

*Frequencies were calculated by using persons from whom information was available, which varied for each question or data point. All values given as no. (%) persons except as indicated. NA, not available; CNS, central nervous system.

Main Article

1Members involved in this study were Patrick Doyle, John Galbraith, Linda Hoang, Pamela Kibsey, Min-Kuang Lee, Sultana Mithani, Marc Romney, and Diane Roscoe.

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