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Volume 16, Number 3—March 2010

CME ACTIVITY

Extensively Drug-Resistant Mycobacterium tuberculosis from Aspirates, Rural South Africa

Earning CME Credit

To obtain credit, you should first read the journal article. After reading the article, you should be able to answer the following, related, multiple-choice questions. To complete the questions and earn continuing medical education (CME) credit, please go to www.medscapecme.com/journal/eid. Credit cannot be obtained for tests completed on paper, although you may use the worksheet below to keep a record of your answers. You must be a registered user on Medscape.com. If you are not registered on Medscape.com, please click on the New Users: Free Registration link on the left hand side of the website to register. Only one answer is correct for each question. Once you successfully answer all post-test questions you will be able to view and/or print your certificate. For questions regarding the content of this activity, contact the accredited provider, CME@medscape.net. For technical assistance, contact CME@webmd.net. American Medical Association’s Physician’s Recognition Award (AMA PRA) credits are accepted in the US as evidence of participation in CME activities. For further information on this award, please refer to http://www.ama-assn.org/ama/pub/category/2922.html. The AMA has determined that physicians not licensed in the US who participate in this CME activity are eligible for AMA PRA Category 1 Credits™. Through agreements that the AMA has made with agencies in some countries, AMA PRA credit is acceptable as evidence of participation in CME activities. If you are not licensed in the US and want to obtain an AMA PRA CME credit, please complete the questions online, print the certificate and present it to your national medical association.

Article Title: Extensively Drug-Resistant Mycobacterium tuberculosis from Aspirates, Rural South Africa

CME Questions

  • Which of the following statements about tuberculosis (TB) infection among patients with concomitant HIV infection is most accurate?

    • A. Smear-positive pulmonary disease and extrapulmonary TB are more common

    • B. Smear-positive pulmonary disease is more common, but extrapulmonary TB is less common

    • C. Smear-negative pulmonary disease and extrapulmonary TB are more common

    • D. Smear-negative pulmonary disease is more common, but extrapulmonary TB is less common

  • Which of the following statements about patients participating in the current study is most accurate?

    • A. Less than 20% were HIV positive

    • B. Pleural fluid cultures were much more common than lymph node cultures

    • C. Most patients had a history of TB

    • D. Approximately one third of lymph node and pleural fluid cultures grew TB

  • In what percentage of patients was the positive lymph node or pleural fluid aspirate culture the only source of a culture diagnosis of TB?

    • A. 5%

    • B. 20%

    • C. 45%

    • D. 75%

  • Which of the following statements about the diagnosis of extensively drug-resistant (XDR) TB is most accurate?

    • A. More than half of cases of XDR TB were diagnosed by fluid aspirate alone

    • B. XDR TB was more common in lymph node vs pleural fluid aspirate cultures

    • C. XDR TB was not discovered in any lymph node aspirate culture

    • D. There was 100% concordance between the growth of XDR TB in sputum and pleural fluid cultures

Activity Evaluation
1. The activity supported the learning objectives.
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2. The material was organized clearly for learning to occur.
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3. The content learned from this activity will impact my practice.
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4. The activity was presented objectively and free of commercial bias.
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