Volume 16, Number 4—April 2010
Panton-Valentine Leukocidin–Positive MRSA, Shanghai
|Strain||Age/sex||Admission month||Onset||Diagnosis†||Resistance pattern‡||Resistance determinants§||ST§||SCCmec||spa type||PFGE|
|D8||1 mo/F||Feb||HA||Pneumonia||Chl, Ery, Gen, Mup||aacA-aphD, ermC, ileS-2||ST30||IV||t318||SH100|
|D9||1 mo/F||Feb||CA||Pneumonia||Gen, Mup||aacA-aphD, ileS-2||–||IV||t318||SH100|
|D16||1 mo/M||Mar||CA||Pneumonia||Gen, Mup||aacA-aphD, ileS-2||–||IV||t318||SH100|
|D7||1 mo/F||Jan||CA||Pneumonia||Ery, Gen||aacA-aphD, ermC||ST88||V||t1376||SH200|
|D18||4 mo/M||Apr||CA||Pneumonia||Ery, Gen||aacA-aphD, ermC||–||V||t1376||SH200|
*Strains are designated by hospital code and strain number. MRSA, methicillin-resistant Staphylococcus aureus; ST, sequence type; SCC, staphylococcal cassette chromosome; spa, staphylococcal protein A; PFGE, pulsed-field gel electrophoresis; HA, healthcare-associated; Chl, chloramphenicol; Ery, erythromycin; Gen, gentamicin, Mup, mupirocin; acA-aphD, aminoglycoside resistance gene encoding the bifunctional enzyme, 6'-aminoglycoside
†According to the diagnosis given in the computerized record. In the 8 children, MRSA was isolated from sputum specimens. One child also had MRSA isolated from pleural fluid. Because limited information was provided in the computerized records, some of the isolations may represent respiratory colonization. The outcomes of the 8 children were unknown.
‡According to disk diffusion test (1,5).
§Determined by PCR as described (4,6). ST30 (allelic profile 2–2-2–2-6–3-2) and ST114 (139–2-2–2-6–139–2) belonged to clonal complex 30.
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