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Volume 16, Number 4—April 2010

Dispatch

Evolution of Porcine Kobuvirus Infection, Hungary

Gábor ReuterComments to Author , Sándor Kecskeméti, and Péter Pankovics
Author affiliations: ÁNTSZ Regional Institute of State Public Health Service, Pécs, Hungary (G. Reuter, P. Pankovics); Central Agricultural Office, Debrecen, Hungary (S. Kecskeméti)

Main Article

Table 2

Natural interhost in vivo mutation changes in sequences of 2 porcine kobuvirus strains, Hungary*

Region Nucleotides
Amino acids
Length Difference % Difference Length Difference % Difference
5′ UTR 576 1 0.17
L 585 15 2.56 195 1 0.51
VP0 1,098 19 1.73 366 3 0.82
VP3 669 8 1.19 223 3 1.34
VP1 762 9 1.18 254 0 0
2A 408 6 1.47 136 2 1.47
2B 585 7 1.19 195 2 1.02
2C 1,005 23 2.28 335 5 1.49
3A 270 6 2.22 90 0 0
3B 102 2 1.96 34 0 0
3C 576 14 2.43 192 2 1.04
3D 1,407 16 1.14 469 2 0.42
3′ UTR 167 1 0.6
Nonstructural† 4,353 74 1.7 1,451 13 0.89
Structural‡ 2,529 36 1.42 843 6 0.71
Complete genome 8,210 127 1.54 2,489 20 0.80

*Strain length shown is for kobuvirus/swine/K-30-HUN/2008/Hungary (accession no. GQ249161) and is compared with prototype strain kobuvirus/swine/S-1-HUN/2007/Hungary (length not shown; accession no. EU787450), from samples collected from pigs on the same farm, November 2008 and February 2007 respectively. UTR, untranslated region; L, leader region.
†2A-3D.
‡VP0–VP1.

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