Volume 16, Number 7—July 2010
Oseltamivir Resistance in Adult Oncology and Hematology Patients Infected with Pandemic (H1N1) 2009 Virus, Australia
|Within 100 days of HSCT‡||No||Yes||No||–|
|Time to development of resistance, d||22||11§||8||4|
|Time of last positive NAT result, d||28||16||8||4|
|Change to zanamivir||Yes||No||No||No|
|Time to zanamivir, d||36||–||–||–|
*HSCT, hematopoietic stem cell transplant; NAT, nucleic acid test; LOS, length of stay.
†Oseltamivir resistance was influenza virus with H275Y mutation.
‡Time from commencement of oseltamivir.
§Detected in bronchoalveolar lavage specimen with negative NAT on nasopharyngeal swab 3 d before first and 10 d after last bronchoscopy. This patient received oseltamivir for 5 d.
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