TY - JOUR AU - Iwamaru, Yoshifumi AU - Imamura, Morikazu AU - Matsuura, Yuichi AU - Masujin, Kentaro AU - Shimizu, Yoshihisa AU - Shu, Yujing AU - Kurachi, Megumi AU - Kasai, Kazuo AU - Murayama, Yuichi AU - Fukuda, Shigeo AU - Onoe, Sadao AU - Hagiwara, Ken’ichi AU - Yamakawa, Yoshio AU - Sata, Tetsutaro AU - Mohri, Shirou AU - Okada, Hiroyuki AU - Yokoyama, Takashi T1 - Accumulation of L-type Bovine Prions in Peripheral Nerve Tissues T2 - Emerging Infectious Disease journal PY - 2010 VL - 16 IS - 7 SP - 1151 SN - 1080-6059 AB - We recently reported the intraspecies transmission of L-type atypical bovine spongiform encephalopathy (BSE). To clarify the peripheral pathogenesis of L-type BSE, we studied prion distribution in nerve and lymphoid tissues obtained from experimentally challenged cattle. As with classical BSE prions, L-type BSE prions accumulated in central and peripheral nerve tissues. KW - atypical bovine spongiform encephalopathy KW - Creutzfeldt-Jacob disease KW - cattle KW - distribution KW - L-type KW - nerve tissues KW - prion KW - neurodegenerative disorder KW - transmissibility KW - zoonoses KW - dispatch KW - Japan DO - 10.3201/eid1607.091882 UR - https://wwwnc.cdc.gov/eid/article/16/7/09-1882_article ER - End of Reference