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Volume 16, Number 8—August 2010

CME ACTIVITY - Research

Correlation of Pandemic (H1N1) 2009 Viral Load with Disease Severity and Prolonged Viral Shedding in Children

Chung-Chen Li1, Lin Wang1, Hock-Liew Eng1, Huey-Ling You, Ling-Sai Chang, Kuo-Shu Tang, Ying-Jui Lin, Hsuan-Chang Kuo, Ing-Kit Lee, Jien-Wei Liu, Eng-Yen Huang, and Kuender D. YangComments to Author 
Author affiliations: Chang Gung Memorial Hospital–Kaohsiung Medical Center, Kaohsiung, Taiwan; Chang Gung University College of Medicine, Kaohsiung

Main Article

Table 1

Demographic data for 581 patients with RT-PCR–confirmed pandemic (H1N1) 2009 virus infection, Taiwan*

Demographic variable
No. (%) patients†
Sex, M/F 337/244
Age, y
Median 10.1
Range 0.38–78.8
<4 49 (8.4)
>4 to <7 87 (15.0)
>7 to <13 256 (44.1)
>13 to <18 130 (22.4)
>18 to <50 54 (9.3)
>50
5 (0.9)
Days after onset of fever
0 (no fever) 8 (1.4)
1 354 (60.9)
2 148 (25.5)
3 49 (8.4)
4 12 (2.1)
5 7 (1.2)
>6
3 (0.5)
Disease severity
URI† 518 (89.2)
Bronchitis 43 (7.4)
Pneumonia 17 (2.9)
Meningoencephalitis
3 (0.5)
Virus load from first throat swab, log10 copies/mL
<1.0 6 (1.0)
1.0– 2.0 47 (8.1)
>2.0 –3.0 80 (13.8)
>3.0 –4.0 170 (29.3)
>4.0–5.0 190 (32.7)
>5.0– 6.0 83 (14.3)
>6.0 5 (0.9)

*RT-PCR, reverse transcription–PCR; URI, upper respiratory tract infection.
†Except as indicated.

Main Article

1These authors contributed equally to this article.

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