TY - JOUR AU - Moorin, Rachael E. AU - Heyworth, Jane S. AU - Forbes, Geoffrey M. AU - Riley, Thomas V. T1 - Long-Term Health Risks for Children and Young Adults after Infective Gastroenteritis T2 - Emerging Infectious Disease journal PY - 2010 VL - 16 IS - 9 SP - 1440 SN - 1080-6059 AB - To quantify the risk and types of sequelae attributable to prior enteric infections, we undertook a population-based retrospective cohort study using linked administrative records. The risk for first-time hospitalization for sequelae was modeled by using Cox proportional regression analysis controlling for other health and sociodemographic factors. We identified a significant increase of 64% in the rate of first-time hospitalization for sequelae for persons with prior enteric infections: 52% for intragastrointestinal sequelae and 63% for extragastrointestinal sequelae compared with first-time hospitalization for those without prior infection. Extragastrointestinal sequelae occurred predominantly during the first 5 years after first-time enteric infection. In contrast, most intragastrointestinal sequelae occurred >10 years later. Infective gastroenteritis during childhood or adolescence increases the risk for first-time hospitalization for intragastrointestinal and extragastrointestinal disease over the 2 decades after first-time enteric infection, highlighting the importance of identifying ways of reducing the incidence of such infections. KW - Gastrointestinal infections KW - sequelae KW - data linkage KW - long-term health risk KW - children KW - adults KW - bacteria KW - research KW - Australia DO - 10.3201/eid1609.081665 UR - https://wwwnc.cdc.gov/eid/article/16/9/08-1665_article ER - End of Reference