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Volume 16, Number 9—September 2010

Research

Trends in Hospitalizations for Peptic Ulcer Disease, United States, 1998–20051

Lydia B. Feinstein2, Robert C. Holman, Krista L. Yorita Christensen, Claudia A. Steiner, and David L. SwerdlowComments to Author 
Author affiliations: Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (L.B. Feinstein, R.C. Holman, K.L. Yorita Christensen, D.L. Swerdlow); Agency for Healthcare Research and Quality, Rockville, Maryland, USA (C.A. Steiner)

Main Article

Table 1

Number of hospitalizations and age-adjusted and age-specific rates of hospitalization for first-listed discharge diagnoses of peptic ulcer disease, overall and by sex, United States, 1998–2005*

Characteristic
Male patients
Female patients
Overall
No. (SE)
Rate† (95% CI)
No. (SE)
Rate† (95% CI)
No. (SE)
Rate† (95% CI)
Age, y
<20 7,851 (320) 2.4 (2.2–2.6) 4,926 (349) 1.6 (1.4–1.8) 12,803 (602) 2.0 (1.8–2.2)
20–44 113,742 (1,344) 27.0 (26.4–27.6) 72,638 (945) 17.5 (17.1–18.0) 186,557 (1,979) 22.3 (21.8–22.8)
45–64 236,381 (2,206) 92.6 (90.9–94.3) 165,013 (1,628) 61.3 (60.2–62.5) 401,581 (3,480) 76.6 (75.3–77.9)
>65
380,016 (3,555)
322.5 (316.6–328.4)

472,590 (4,224)
283.6 (278.6–288.6)

852,720 (7,409)
299.8 (294.7–304.9)
Race/ethnicity‡
White 392,199 (5,508) 48.7 (47.7–49.6) 408,120 (5,712) 40.4 (39.5–41.2) 800,358 (10,974) 44.2 (43.3–45.0)
Black 70,453 (1,968) 69.7 (67.1–72.3) 59,045 (1,733) 46.4 (44.5–48.2) 129,499 (3,577) 56.8 (54.7–58.8)
Hispanic 48,076 (1,661) 58.4 (55.1–61.7) 33,179 (1,324) 38.7 (36.1–41.2) 81,270 (2,887) 48.0 (45.3–50.8)
Asian/Pacific Islander
23,268 (1,158)
68.2 (63.0–73.5)

14,789 (767)
38.1 (34.7–41.6)

38,056 (1,846)
51.8 (47.8–55.8)
Ulcer type
Gastric 343,079 (3,011) 33.5 (33.1–34.0) 427,469 (3,750) 33.6 (33.1–34.0) 770,785 (6,347) 33.7 (33.3–34.2)
Peptic 40,009 (678) 3.8 (3.7–3.9) 51,452 (818) 4.1 (4.0–4.2) 91,524 (1,313) 4.0 (3.9–4.1)
Duodenal 340,161 2,973 33.1 (32.9–33.5) 217,946 (2,055) 17.1 (16.8–17.4) 558,443 (4,676) 24.4 (24.1–24.7)
Gastrojejunal
14,772 (335)
1.4 (1.4–1.5)

18,336 (504)
1.5 (1.4–1.6)

33,142 (699)
1.4 (1.4–1.5)
Total 738,020 (5,897) 71.9 (71.0–72.7) 715,203 (5,824) 56.3 (55.6–57.0) 1,453,892 (11,201) 63.6 (62.9–64.3)

*Diagnosis codes 531–534 from the International Classification of Diseases, 9th Revision, Clinical Modification. National estimates determined by using the Nationwide Inpatient Sample (21).
†Per 100,000 population.
‡Race/ethnicity was missing for 26.0% of hospitalized patients. Data were insufficient for the race/ethnicity category of American Indian/Alaska Native.

Main Article

1Presented in part at the Annual Interscience Conference on Antimicrobial Agents and Chemotherapy and Infectious Diseases Society of America; 2008 Oct 28; Washington, DC (abstract number L-4129).

2Current affiliation: University of North Carolina, Chapel Hill, North Carolina, USA.

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