Volume 16, Number 9—September 2010
Research
Trends in Hospitalizations for Peptic Ulcer Disease, United States, 1998–20051
Table 2
Number of hospitalizations and the age-adjusted and age-specific hospitalization rates for first-listed discharge diagnoses of peptic ulcer disease, United States, 1998–2005*
| Characteristic | 1998 |
2005 |
% Rate change | β-coefficient‡ | |||
|---|---|---|---|---|---|---|---|
| No. (SE) | Rate† (95% CI) | No. (SE) | Rate† (95% CI) | ||||
| Age, y | |||||||
| <20 | 1,524 (133) | 1.9 (1.6–2.2) | 1,924 (290) | 2.4 (1.7–3.0) | +26 | 0.016§ | |
| 20–44 | 26,420 (817) | 25.5 (23.9–27.0) | 21,523 (656) | 20.5 (19.3–21.7) | −20 | −0.648¶ | |
| 45–64 | 50,446 (1,164) | 86.6 (82.7–90.5) | 50,993 (1,326) | 70.0 (66.4–73.6) | −19 | −1.911¶ | |
| ≥6>65 |
115,181 (2,750) |
332.7 (317.1–348.3) |
95,349 (2,449) |
259.2 (246.1–272.2) |
−22 |
−8.759¶ |
|
| Sex | |||||||
| M | 100,721 (2,159) | 83.1 (80.4–85.6) | 84,883 (2,013) | 62.2 (59.9–64.4) | −25 | −2.164¶ | |
| F |
92,831 (2,080) |
60.8 (58.7–62.9) |
84,808 (2,040) |
51.3 (49.5–53.2) |
−16 |
−0.886¶ |
|
| Race/ethnicity# | |||||||
| White | 111,092 (4,086) | 50.3 (47.7–52.9) | 91,939 (3,765) | 39.5 (37.3–41.8) | −22 | −1.696¶ | |
| Black | 18,188 (1,428) | 68.6 (61.7–75.6) | 12,794 (899) | 41.4 (37.5–45.4) | −40 | −2.093¶ | |
| Hispanic | 10,850 (1,310) | 63.3 (50.7–75.9) | 11,079 (1,034) | 43.4 (37.3–49.6) | −31 | 0.308§ | |
| Asian/Pacific Islander |
4,526 (673) |
59.7 (45.4–73.9) |
4,220 (520) |
38.2 (30.9–45.4) |
−36 |
−1.620** |
|
| Region | |||||||
| Northeast | 33,578 (1,746) | 60.1 (55.5–64.7) | 29,046 (1,740) | 49.3 (45.1–53.6) | −18 | −1.697¶ | |
| Midwest | 44,910 (1,909) | 70.1 (65.5–74.7) | 39,097 (1,562) | 57.5 (53.8–61.1) | −18 | −0.964** | |
| South | 76,773 (2,551) | 79.5 (75.6–83.4) | 66,969 (2,711) | 61.3 (57.8–64.8) | −23 | −2.046¶ | |
| West |
38,315 (1,707) |
68.9 (64.2–73.7) |
34,746 (1,519) |
53.8 (50.2–57.3) |
−22 |
−1.129†† |
|
| Total | 193,576 (4,014) | 71.1 (68.9–73.4) | 169,858 (3,889) | 56.5 (54.6–58.3) | −21 | −1.501¶ | |
*Diagnosis codes 531–534 from the International Classification of Diseases, 9th Revision, Clinical Modification. National estimates were determined by using the Nationwide Inpatient Sample (21).
†Per 100,000 population.
‡β-coefficient from linear regression analysis, using a weighted least-squares technique, of the annual rate over the years of the study period. The p value corresponds to the test of the null hypothesis that the coefficient for year is zero.
§ p>0.05.
¶p<0.001.
#Race/ethnicity was missing for 26.0% of the hospitalizations. Data were insufficient for the race/ethnicity category American Indian/Alaska Native.
**0.01<p<0.05.
††0.001<p<0.01.
1Presented in part at the Annual Interscience Conference on Antimicrobial Agents and Chemotherapy and Infectious Diseases Society of America; 2008 Oct 28; Washington, DC (abstract number L-4129).
2Current affiliation: University of North Carolina, Chapel Hill, North Carolina, USA.
