Volume 16, Number 9—September 2010
Research
Trends in Hospitalizations for Peptic Ulcer Disease, United States, 1998–20051
Table 3
Number of hospitalizations and the age-adjusted and age-specific hospitalization rates for any-listed discharge diagnoses that included Helicobacter pylori infection, United States, 1998–2005*
| Characteristic | 1998 |
2005 |
% Rate change | β-coefficient‡ | |||
|---|---|---|---|---|---|---|---|
| No. (SE) | Rate† (95% CI) | No. (SE) | Rate† (95% CI) | ||||
| Age, y | |||||||
| <20 | 1,320 (151) | 1.7 (1.3–2.0) | 1,718 (276) | 2.1 (1.4–2.8) | +24 | 0.040§ | |
| 20–44 | 14,617 (648) | 14.1 (12.9–15.3) | 10,391 (457) | 9.9 (9.0–10.7) | −30 | −0.436¶ | |
| 45–64 | 25,287 (955) | 43.4 (40.2–46.6) | 17,923 (724) | 24.6 (22.7–26.6) | −43 | −2.265¶ | |
| >65 |
56,593 (1,866) |
163.5 (152.9–174.0) |
27,733 (1,009) |
75.4 (70.0–80.8) |
−54 |
−10.647¶ |
|
| Sex | |||||||
| M | 47,162 (1,450) | 38.9 (37.2–40.6) | 28,535 (946) | 20.6 (19.6–21.6) | −47 | −1.854¶ | |
| F |
50,656 (1,830) |
33.4 (31.7–35.0) |
29,220 (1,078) |
18.0 (17.0–18.9) |
−46 |
−1.909¶ |
|
| Race/ethnicity# | |||||||
| White | 51,235 (2,353) | 23.2 (21.7–24.7) | 23,735 (1,117) | 10.3 (9.6–11.0) | −56 | −1.649¶ | |
| Black | 11,724 (887) | 44.1 (39.7–48.6) | 7,480 (561) | 23.6 (21.1–26.1) | −47 | −1.926¶ | |
| Hispanic | 7,305 (839) | 41.8 (34.0–49.6) | 7,075 (720) | 24.5 (21.1–27.9) | −41 | 0.131§ | |
| Asian/Pacific Islander |
2,563 (361) |
34.0 (26.2–41.9) |
1,771 (252) |
15.8 (12.0–19.6) |
−54 |
−1.471¶ |
|
| Region | |||||||
| Northeast | 17,551 (1,588) | 31.4 (27.8–35.1) | 11,285 (681) | 19.3 (17.6–21.0) | −39 | −1.392¶ | |
| Midwest | 23,644 (1,430) | 36.9 (33.6–40.2) | 12,116 (722) | 17.9 (16.3–19.5) | −52 | −2.229¶ | |
| South | 37,929 (2,100) | 39.3 (36.4–42.1) | 23,603 (1,476) | 21.6 (19.8–23.4) | −45 | −2.193¶ | |
| West |
18,699 (1,038) |
33.6 (30.8–36.3) |
10,766 (738) |
16.5 (14.8–18.1) |
−51 |
−1.493¶ |
|
| Total | 97,823 (3,156) | 35.9 (34.3–37.5) | 57,770 (1,925) | 19.2 (18.3–20.1) | −47 | −1.884¶ | |
*Diagnosis codes 41.86 from the International Classification of Diseases, 9th Revision, Clinical Modification. National estimates were determined by using the Nationwide Inpatient Sample (21). All H. pylori diagnoses are 1 of as many as 15 diagnoses.
†Per 100,000 population.
‡β-coefficient from linear regression analysis, using a weighted least-squares technique, of the annual rate over the years of the study period. The p value corresponds to the test of the null hypothesis that the coefficient for year is zero.
§p≥0.05.
¶p<0.001.
#Race/ethnicity was missing for 26.0% of the patients hospitalized. Data were insufficient for the race/ethnicity category American Indian/Alaska Native.
1Presented in part at the Annual Interscience Conference on Antimicrobial Agents and Chemotherapy and Infectious Diseases Society of America; 2008 Oct 28; Washington, DC (abstract number L-4129).
2Current affiliation: University of North Carolina, Chapel Hill, North Carolina, USA.
