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Volume 16, Number 9—September 2010

Research

Worldwide Diversity of Klebsiella pneumoniae That Produce β-Lactamase blaKPC-2 Gene1

Gaëlle Cuzon, Thierry NaasComments to Author , HaVy Truong, Maria-Virginia Villegas, Karin T. Wisell, Yehuda Carmeli, Ana. C. Gales, Shiri Navon-Venezia, John P. Quinn, and Patrice Nordmann
Author affiliations: Author affiliations: Institut National de la Santé et de la Recherche Médicale, Paris, France (G. Cuzon, T. Naas, H. Truong, P. Nordmann); International Center for Medical Research and Training, Cali, Colombia (M.V. Villegas); Swedish Institute for Infectious Disease Control, Stockholm, Sweden (K.T. Wisell); Sourasky Medical Center, Tel Aviv, Israel (Y. Carmeli, S. Navon-Venezia); Universidade Federal de São Paulo, São Paulo, Brazil (A.C. Gales); John H. Stroger Jr. Hospital of Cook County, Chicago, Illinois, USA (J.P. Quinn); Chicago Infectious Disease Research Institute, Chicago (J.P. Quinn)

Main Article

Table 3

Plasmid analysis, pulsotype, and sequence type of Klebsiella pneumoniae isolates from 5 countries*

Isolate no. Isolate name Plasmids
PFGE type MLST
ST
Size, kb Inc gap infB mdh pgi phoE rpo tonB
1 YC 80 FiiAS A 3 3 1 1 1 1 79 258
2 GR 80 FiiAS A 3 3 1 1 1 1 79 258
3 K271 80 FiiAS A 3 3 1 1 1 1 79 258
4 KN2303 75, 35 N B 2 1 11 1 1 1 13 337
5 KN633 12 ND C 17 19 22† 39 34† 21 52 338
6 INC H1521-6 75 L/M D 1 6 1 1 1 1 1 14
7 INC H1516-6 75 L/M D 1 6 1 1 1 1 1 14
8 HPTU 27635 35 L/M E 18 15 25† 24 11† 13 51 339
9 HPTU 2020532 12 ND C 17 19 22† 39 34† 21 52 338
10 A28006 12 L/M F 3 3 1 1 1 1 4 11
11 A28008 12 L/M F 3 3 1 1 1 1 4 11
12 A28009 12 L/M F 3 3 1 1 1 1 4 11
13 A28011 12 L/M F 3 3 1 1 1 1 4 11
14 A33504 50 ND G 3 3 1 1 1 1 4 11
15 475 80 N H 3 1 1 1 1 1 43 277
16 588 70 N I 3 3 1 1 1 1 18 340

*Countries shown in Table 1. PFGE, pulsed-field gel electrophoresis; MLST, multilocus sequence type; ST, sequence type; ND, could not be determined with the Inc primers tested.
†Alleles are variants of previously described alleles (Figure 2).

Main Article

1This study was presented in part at the Interscience Conference on Antimicrobial Agents and Chemotherapy; 2009 Sep 12–15; San Francisco, CA, USA.

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