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Volume 16, Number 9—September 2010

Research

Determinants of Multidrug-Resistant Tuberculosis Clusters, California, USA, 2004–2007

John Z. MetcalfeComments to Author , Elizabeth Y. Kim, S.-Y. Grace Lin, Adithya Cattamanchi, Peter Oh, Jennifer Flood, Philip C. Hopewell, and Midori Kato-Maeda
Author affiliations: Author affiliations: University of California, San Francisco, California, USA (J.Z. Metcalfe, E.Y. Kim, A. Cattamanchi, P.C. Hopewell, M. Kato-Maeda); California Department of Public Health, Richmond, California, USA (S.-Y.G. Lin, P. Oh, J. Flood)

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Table 4

Univariate associations of phylogeographic lineage with 112 clustered and nonclustered MDR TB infections, California, USA, 2004–2007*

Strain lineage Nonclustered, n = 87, no. (%) Clustered, n = 25, no. (%) OR (95% CI) p value
East-Asian 37 (43) 17 (68) 2.87 (1.03–8.48) 0.04
Euro-American 26 (30) 8 (32) 1.10 (0.36–3.12) 0.81
Indo-Oceanic 21 (24) 0 0.003
East African–Indian 3 (4) 0 1.0

*N = 112. Lineage could not be established by spoligotyping for 11 (8.9%) cases. MDR, multidrug-resistant tuberculosis; OR, odds ratio; CI, confidence interval.

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